Predicting Outcomes in Posttransplant Diabetes Mellitus Via microRNA

Phase

N/A

Condition

Diabetes Prevention

Diabetes And Hypertension

Treatment

N/A

Clinical Study ID

NCT07055984

University hospital Martin

Ages > 18
All Genders

Study Summary

The study aims to improve the prediction and early detection of post-transplant diabetes mellitus (PTDM) in kidney transplant recipients. The investigators are investigating whether specific microRNA profiles measured 3 months after transplantation can reliably predict the development of PTDM within the following one to two years.

Additionally, the investigators are evaluating how traditional risk factors-such as age, immunosuppressive therapy, obesity, and infections like CMV-interact with these microRNA markers.

The ultimate goal of this research is to identify early indicators of blood sugar issues, enabling timely interventions to improve health outcomes and personalize patient care after kidney transplantation.

Eligibility Criteria

Inclusion

Inclusion Criteria:

Adult patients undergoing kidney transplantation.
Absence of pre-existing type 1 or type 2 diabetes mellitus.
Willingness to provide informed consent and comply with study procedures.

Exclusion

Exclusion Criteria:

Pre-existing type 1 or type 2 diabetes mellitus.
Previous organ transplantation.
Severe comorbidities that could confound the assessment of PTDM (e.g., pancreaticdisease).
Inability to provide informed consent.

Study Design

April 28, 2025

April 28, 2029

Connect with a study center

Transplant-nephorlogy department
Martin, 03601
Slovakia
Active - Recruiting
University hospital Martin
Martin, 03601
Slovakia
Active - Recruiting

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.