A Study of Brenipatide in Adult Participants With Schizophrenia

Inclusion Criteria:

• Meet the diagnostic criteria of schizophrenia

• Are on a stable standard of care medication regimen for schizophrenia

• If the duration of illness is >6 years, participant has experienced at least onerelapse of schizophrenia in last 3 years

• Have at least 1 reliable study partner (for example, a family member, social worker,caseworker, residential facility staff, or nurse)

• Are reliable and willing to make themselves available for the duration of the studyand attend required study visits, and are willing and able to follow studyprocedures as required, such as

• self-inject study intervention store and use the provided study intervention asdirected,

• maintain electronic or paper study diaries, as applicable, and

• complete the required questionnaires

Exclusion Criteria:

• Have lifetime history of bipolar disorder, borderline personality disorder, or anyeating disorder

• Evidence of moderate or severe substance or alcohol use disorder within 180 days ofscreening

• Have type 1 diabetes, or history of ketoacidosis or hyperosmolar state or coma

• Are actively suicidal or deemed to be a significant risk for suicide

• Are currently enrolled in any other clinical study involving an investigationalproduct or any other type of medical research judged not to be scientifically ormedically compatible with this study