Phase
Condition
Macular Degeneration
Glaucoma
Geographic Atrophy
Treatment
N/AClinical Study ID
Ages > 50 All Genders Accepts Healthy Volunteers
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Men and women aged over 50 years
Ametropia of less than 6 diopters and anisometropia of less than 2 diopters
Clear non-lenticular ocular media AMD patients:
Patients with nonexudative AMD
Visual acuity in the study eye > 20/60 Glaucoma patients:
Unilateral or bilateral primary open angle glaucoma
At least 3 reliable visual field testings
Treated intraocular pressure < 21 mmHg,
Visual field mean deviation MD <10 (Humphrey 30-2) Healthy control subjects:
Age- , gender- and sex- matched to the two patient groups,
Matched with regard to smoking habits of the two patient group
No observable eye diseases
Exclusion
Exclusion Criteria:
History or presence of gastrointestinal, liver or kidney disease, or other conditionsknown to interfere with distribution, metabolism or excretion of the study drug
Blood donation during the previous 3 weeks
Abuse of alcoholic beverages or drugs, participation in a clinical trial in the 3weeks preceding the study
Known diabetes mellitus
Presence of any ocular pathology that interferes with the aims of the present study
Intraocular surgery within the last 3 weeks
Hypersensitivity to moxaverine
Acute gastric bleeding, massive cerebral hemorrhage related to stroke
Study Design
Connect with a study center
Department of Clinical Pharmacology, Medical University of Vienna
Vienna, 1090
AustriaSite Not Available
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