Early Enteral Feeding After Pylorus Preserving Pancreatoduodenectomy

Last updated: December 15, 2008
Sponsor: Yonsei University
Overall Status: Trial Status Unknown

Phase

3

Condition

Gall Bladder Cancer

Digestive System Neoplasms

Liver Cancer

Treatment

N/A

Clinical Study ID

NCT00809081
EN Vs PN
  • Ages 18-85
  • All Genders

Study Summary

Pancreaticoduodenectomy is associated with a high incidence of postoperative complications. These postoperative complications could delay postoperative resumption of adequate oral intake. Clinical study on postoperative feeding after pancreaticoduodenectomy is very limited. Method of Nutritional support (Enteral feeding or total parenteral support)after pancreaticoduodenectomy is controversial.

  1. To evaluate whether early enteral nutrition may be a suitable alternative to total parenteral nutrition

  2. To evaluate whether enteral feeding improve nutritional status after pancreaticoduodenectomy

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Periampullar carcinoma

  • Pancreaticoduonectomy

  • KARNOFSKY PERFORMANCE SCALE > 70

  • No history of Major operation

Exclusion

Exclusion Criteria:

  • Creatinine level>3mg/L

  • Ascitis/portal hypertension

  • New York Heart Association class>3

  • COPD

  • Preoperative Radiotheraly/chemotherapy

  • Unresectable primary cancer

  • Palliative surgery

Study Design

Total Participants: 38
Study Start date:
July 01, 2007
Estimated Completion Date:
January 31, 2010

Study Description

Pancreaticoduodenectomy is associated with a high incidence of postoperative complications. These postoperative complications could delay postoperative resumption of adequate oral intake. The use of TPN significantly increases postoperative complications, especially those associate with infections. However, method of Nutritional support (Enteral feeding or total parenteral support)after pancreaticoduodenectomy is controversial.

  1. To evaluate whether early enteral nutrition may be decreased the postoperative complications

  2. To evaluate whether enteral feeding improve nutritional status after pancreaticoduodenectomy

  3. To determine the optimal method for postoperative nutritional support

Connect with a study center

  • Yongdong Severance Hospital

    Seoul,
    Korea, Republic of

    Active - Recruiting

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.