The Effects of Polyphenol-rich Berry Juice on Blood Pressure in Hypertensive Subjects

Last updated: June 29, 2012
Sponsor: University of Oslo
Overall Status: Completed

Phase

3

Condition

Vascular Diseases

Williams Syndrome

Stress

Treatment

N/A

Clinical Study ID

NCT01568983
Optijuice
  • Ages 50-70
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

The purpose of this study is to investigate the effects of berry juices containing different levels of polyphenols on blood pressure and other cardiovascular risk factors.

The study is a 12 week double blinded randomized controlled intervention trial. The subjects will be divided in three groups where one receives a placebo juice while the two other will consume 0.5 liter of juice containing different levels of polyphenols. Blood pressure will be monitored and blood samples will be taken.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Pre-hypertension or hypertension systolic blood pressure in the 130-179 mmHg rangeand/or diastolic blood pressure in the 85-109 mmHg range)

  • BMI 20-35 kg/m2

  • Stable weight (change <4 kg previous 12 weeks)

Exclusion

Exclusion Criteria:

  • Regular use of blood pressure lowering agens

  • Diabetes type I or II

  • Smokers

  • Allergy to grape, cherries, blueberries/bilberries, black currant, aronia

  • Supplements for weight loss

  • Changes in pharmacological treatment of hyperlipidemia or hyperglycemia (initiation,termination or changes in dosage) last 30 days prior to inclusion or during the studyperiod (run-in and intervention)

  • Participation in a drug trial during the previous 30 days

Study Design

Total Participants: 153
Study Start date:
December 01, 2011
Estimated Completion Date:
June 30, 2012

Connect with a study center

  • University of Oslo

    Oslo,
    Norway

    Site Not Available

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