Phase
Condition
Common Cold
Allergy
Nasal Obstruction
Treatment
Desloratadine 5 mg
Placebo
Clinical Study ID
Ages > 16 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Has at least a 2-year history of seasonal allergic rhinitis with typical symptoms
Male or female who is unlikely to conceive: a surgically sterilized female, femalewho has reached natural menopause, or is of reproductive potential and agrees toeither remain abstinent or use (or have her partner use) 2 acceptable methods ofbirth control from study start through 14 days after the last dose of study drug.
Exclusion
Exclusion Criteria:
Has a lower respiratory tract infection or has a nasopharyngolaryngeal infection (acute upper respiratory tract infection, acute pharyngolaryngitis, or acutetonsillitis, etc.) requiring treatment
Has a coexisting infection or systemic mycosis for which there are no effectiveantibiotics
Has asthma that is under treatment and/or uncontrolled
Has nasal septum ulcers, nasal surgery, or nasal trauma which have not healed
Has vasomotor rhinitis or eosinophilic rhinitis
Has a history of hypersensitivity to antihistamines or ingredients of study drug
Has had treatment with corticosteroids (oral, injectable, suppository, depot drugs [injectable]) or immunological drugs within 28 days prior to Visit 2
Is currently receiving treatment with another investigational drug or has receivedan investigational drug within prior 3 months
Has started specific desensitization therapy (allergen immunotherapy) or nonspecificallassotherapy (Histaglobin, vaccine therapy, etc.) or who has received suchtherapies within prior 3 months
Has received coagulation or resection using laser therapy etc. for treatment fornasal symptoms
Will receive nasal nebulizer therapy and/or thermotherapy during study period
Has severe hepatic, renal, cardiac, hematological disease, or other seriouscoexisting diseases and whose general condition is poor
Has a history of malignancy or clinically important hematological disorder, exceptfor adequately treated non-melanomatous skin carcinoma or carcinoma in situ of thecervix
Has a history of severe drug allergy (e.g. anaphylactoid reaction)
Is pregnant or lactating or may be pregnant
Is planning a remote trip for more than 1 day during the Symptom Confirmation Periodor for more than 2 days during the Treatment Period.
Study Design
Study Description
Connect with a study center
MSD K.K
Chiyoda-Ku, Tokyo 102-8667
JapanSite Not Available
MSD K.K.
Chiyoda-Ku, Tokyo, 102-8667
JapanSite Not Available
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