Finding LCX AMI With Posterior ECG LeadS

Last updated: March 26, 2019
Sponsor: Rigshospitalet, Denmark
Overall Status: Active - Recruiting

Phase

N/A

Condition

Circulation Disorders

Occlusions

Congestive Heart Failure

Treatment

N/A

Clinical Study ID

NCT02788799
FLAWLESS-16-YF
  • All Genders

Study Summary

Along with symptoms of chest pain, the presence of ST segment elevations on ECG is the criterion usually used in practice to identify patients with acute coronary artery occlusion and is essential for the direct and acute referral of patients for primary PCI. However, ECG does not always reflect changes in the posterior wall of the heart, often equivalent to the left circumflex coronary artery's (LCX) supply area, resulting in an underrepresentation of LCX as culprit artery in STEMI populations. There is a general concern that some patients with genuine acute occlusion of LCX may present without ST segment elevation and be denied reperfusion therapy, resulting in larger infarction and worse outcome.

The aim of this trial is to implement record of posterior ECG leads (V7, V8 and V9) in addition to the standard 12-lead ECG in the pre-hospital setting and to evaluate the clinical impact of this implementation: In comparison to a control cohort of STEMI patients diagnosed with a pre-hospital standard 12-lead ECG prior study start, the investigators hypothesize that introducing V7-V9 leads as a clinical routine in the pre-hospital setting will identify patients with STEMI involving LCX and with a non-diagnostic standard 12-lead ECG.

Eligibility Criteria

Inclusion

Inclusion Criteria: Intervention group:

  • All STEMI patients referred directly from the pre-hospital setting, treated withprimary PCI and with available standard 12-lead ECG and ECG with V7-V9 leads.

Exclusion

Exclusion Criteria:

  • STEMI patients treated with primary PCI and no ECG with V7-V9 leads.

Study Design

Total Participants: 1200
Study Start date:
February 01, 2017
Estimated Completion Date:
December 31, 2019

Connect with a study center

  • Rigshospitalet

    Copenhagen,
    Denmark

    Active - Recruiting

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