Glucosamine Sulphate and Ginkgo Biloba as Antifungal Activity for Treating Tinea Pedis

Last updated: October 9, 2019
Sponsor: Ahmed A. H. Abdellatif
Overall Status: Active - Recruiting

Phase

1

Condition

Fungal Infections

Athlete's Foot (Tinea Pedis)

Yeast Infections

Treatment

N/A

Clinical Study ID

NCT02882438
AlAzharGGATP
  • Ages 20-40
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

Tinea Pedis infected the feet of about 20-25% of the world population. Tinea Pedis is a fungal infection of the feet and it is easily spread. Oral therapy is usually used for chronic conditions or when topical treatment has failed. The aim of this study is to prove the antifungal and antibacterial activity of Ginko Biloba (GKB) & Glucosamine (GL) as separate material or both in combination.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • It is important to follow up and collect data, preferably for six months for local andsystemic activity of Ginkgo Biloba and Glucosamine, to establish whether the infectionrecurrent or not.

Exclusion

Exclusion Criteria:

  • Larger numbers of participants having different kind of fungal infection are needed totest efficiency drug in order to produce more reliable data.

Study Design

Total Participants: 30
Study Start date:
January 01, 2016
Estimated Completion Date:
October 31, 2022

Study Description

Ginko Biloba (GKB) & Glucosamine (GL) were formulated in different dosage forms such as capsules, hydrogel and spray. GKB&GL were in filled in hard gelatin capsules as three formulae (GKB caps, GL caps and both as mixture in caps). Also, GKB&GL were formulated in hydrogel using 2% carbopol 934 as three formulae (GKB only, GL only and both as mixture). The same also were formulated as spray using alcohol, water and glycerol in concentration of 60%, 20% and 20% respectively. The study included 5 trials, involving 35 participants. The oral formulae were tried on 30 participants having Tenia Pedis. Fluconazole was as standard antifungal drug.The antifungal activity of all gel formulae was determined by Agar well-diffusion method. It is also important to follow up and collect data, preferably for six months for local and systemic activity, to establish whether or not the infection recurred or not. In future clinical trials, research should consider the costs of the different treatment approaches.

Connect with a study center

  • Assiut Clinic

    Assiut, 71526
    Egypt

    Active - Recruiting

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