Establishment of a Parathyroid Tissue Bank

Last updated: January 24, 2020
Sponsor: M.D. Anderson Cancer Center
Overall Status: Active - Recruiting

Phase

N/A

Condition

Parathyroid Disease

Parathyroid Disorders

Treatment

N/A

Clinical Study ID

NCT03051126
LAB08-0034
  • All Genders

Study Summary

To develop a tissue bank library for patients with parathyroid disease who have undergone surgery and/or biopsy, and/or who may undergo surgical intervention at M. D. Anderson Cancer Center or outside centers, and/or all patients seen through the Parathyroid Center at participating sites, whether or not the patients undergo treatment for their disease. The tissue bank will contain both normal parathyroid tissue and diseased tissue, and will provide a resource for the ongoing study of parathyroid disease and management.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Eligible participants will include patients presenting at MD Anderson Cancer who arescheduled for surgical treatment of parathyroid disease and/or patients with MEN1,and/or those presenting with hyperparathyroidism and/or pancreatic lesion, who arescheduled for pancreas tumor intervention, as well as patients having had surgery andwho have had residual tissue stored under LAB02-518, LAB03-0320 or prior front doorconsents, or who have had surgery at other centers and provide signed authorization toobtain the tissue from the outside institution.

  2. In addition, eligible participants may include family members of MD Anderson patientswho have been diagnosed with parathyroid disease and who have had surgery at othercenters, and who provide a signed authorization to obtain the tissue from outsidefacilities AND/OR who begin care at MD Anderson and will be having intervention at MDAnderson.

Exclusion

Exclusion Criteria: N/A

Study Design

Total Participants: 10000
Study Start date:
July 09, 2009
Estimated Completion Date:
July 01, 2025

Study Description

Fresh residual tissue samples will be obtained during parathyroid and/or pancreas tumor intervention (for pancreas tumor intervention in MEN1 patients with hyperparathyroidism and pancreatic lesions).

In addition, outside paraffin tissue blocks or slides will be requested from patients presenting to MDACC, or to participating family members who have had prior surgery outside of MD Anderson.

Forty cubic centimeters (40 ccs) of whole blood will be obtained from individuals for peripheral blood lymphocyte, plasma, and serum separation and analysis per event. Collections may be made at any or all of the following timepoints: preoperatively, during intervention, and/or at subsequent follow-up visits for up to fifteen years.

Connect with a study center

  • University of Texas MD Anderson Cancer Center

    Houston, Texas 77030
    United States

    Active - Recruiting

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