The Genetics of Pulmonary Fibrosis

Last updated: March 24, 2025
Sponsor: University of Colorado, Denver
Overall Status: Active - Recruiting

Phase

N/A

Condition

Idiopathic Pulmonary Fibrosis

Cystic Fibrosis

Lung Injury

Treatment

Blood draw

Questionnaire

Clinical Study ID

NCT03478553
15-1147
W81XWH-17-1-0597_1a
  • Ages > 18
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

This study seeks to screen first degree family members of people with Idiopathic Pulmonary Fibrosis (IPF) for the earliest signs of lung fibrosis.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age at least 18 years old

  • Family member diagnosed with IPF

Exclusion

Exclusion Criteria:

  • No family member with IPF

Study Design

Total Participants: 1000
Treatment Group(s): 2
Primary Treatment: Blood draw
Phase:
Study Start date:
January 18, 2018
Estimated Completion Date:
December 31, 2026

Study Description

The purpose of this study is to explore genetic factors associated with the development of pulmonary fibrosis. The investigators aim is to identify and explore genetic loci that affect development of pulmonary fibrosis and also explore related environmental exposures. Idiopathic pulmonary fibrosis (IPF) is one of the interstitial lung diseases under the broader umbrella of idiopathic interstitial pneumonias (IIP). The investigators hypothesize that inherited genetic factors are associated with pulmonary fibrosis. To investigate the genetics of pulmonary fibrosis, the investigators plan to enroll individuals with pulmonary fibrosis and their family members.

Connect with a study center

  • University of Colorado Anschutz Medical Campus

    Aurora, Colorado 80045
    United States

    Active - Recruiting

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