Belgian Central Sleep Apnea REgistry

Last updated: July 2, 2024
Sponsor: Universitaire Ziekenhuizen KU Leuven
Overall Status: Active - Recruiting

Phase

N/A

Condition

Sleep Apnea Syndromes

Treatment

No intervention

Clinical Study ID

NCT03621566
B322201835950
  • Ages > 18
  • All Genders

Study Summary

This study evaluates different factors that determine the treatment choice and treatment compliance in patients with central sleep apnea. All patients will receive routine care (registry).

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age ≥ 18 years old

  • An apnea/hypopnea index ≥ 15/h of sleep and proportion of non-obstructive events > 50%, derived from polysomnography (diagnostic or during (PAP) treatment)

  • Written informed consent provided

Exclusion

Exclusion Criteria:

  • Patients with mental disability making it impossible to understand the studyprotocol

Study Design

Total Participants: 1500
Treatment Group(s): 1
Primary Treatment: No intervention
Phase:
Study Start date:
June 25, 2018
Estimated Completion Date:
June 25, 2028

Study Description

Central sleep apnea (CSA) is characterized by intermittent cessation or decrease of airflow and effort of breathing during sleep. The diagnostic criteria for CSA varies according to the type of CSA (e.g. CSA due to cardiac failure, due to a medication, ...).

CSA is defined as: (1) an apnea/hypopnea index ≥ 15 per hour of sleep and (2) the number of central apneas and/or hypopneas is > 50% of the total number of apneas and hypopneas.

Presence of CSA is associated with excessive daytime sleepiness and poor sleep quality. Furthermore, in patients with heart failure, presence of CSA was found to be related to mortality. As yet, however, there is insufficient knowledge on the clinical features, pathophysiological background and consecutive algorithms for treatment. Currently, it is not fully clear whether CSA or the treatment of CSA is related to disease progress.

The aim of this trial is to evaluate the current treatment choices for CSA in Belgium and compliance with and effects of these treatments.

Connect with a study center

  • OLV Ziekenhuis

    Aalst, 9300
    Belgium

    Active - Recruiting

  • UZA

    Antwerp, 2650
    Belgium

    Active - Recruiting

  • ZNA Middelheim

    Antwerp, 2020
    Belgium

    Active - Recruiting

  • AZ Sint-Jan

    Brugge, 8000
    Belgium

    Active - Recruiting

  • CHU Saint-Pierre

    Brussels, 1000
    Belgium

    Active - Recruiting

  • Ghent University Hospital

    Ghent, 9000
    Belgium

    Active - Recruiting

  • Jessa Ziekenhuis

    Hasselt, 3500
    Belgium

    Active - Recruiting

  • AZ Groeninge

    Kortrijk, 8500
    Belgium

    Active - Recruiting

  • CH Jolimont

    La Louvière, 7100
    Belgium

    Active - Recruiting

  • UZ Leuven

    Leuven, 3000
    Belgium

    Active - Recruiting

  • CHR de la Citadelle

    Liège, 4000
    Belgium

    Active - Recruiting

  • CHU UCL Namur

    Namur, 5530
    Belgium

    Active - Recruiting

  • AZ Glorieux

    Ronse, 9600
    Belgium

    Active - Recruiting

  • AZ Turnhout

    Turnhout, 2300
    Belgium

    Active - Recruiting

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