Effectiveness Inspirational Muscle Training

Last updated: May 9, 2023
Sponsor: Universidade Federal do vale do São Francisco
Overall Status: Active - Recruiting

Phase

N/A

Condition

Lung Injury

Respiratory Failure

Treatment

Inspiratory Muscle Training (IMT)

Intensive Physiotherapy (IPT)

Clinical Study ID

NCT03758573
IMT
  • Ages > 18
  • All Genders

Study Summary

The long stay in mechanical ventilation can induce several complications, among them respiratory muscle weakness, this has been related to the duration of mechanical ventilation, delay and failure to wean, resulting in longer hospitalization, which reflects in greater care increase in hospital costs. Therefore, of this research will be to compare the effectiveness of early inspiratory muscle training (IMT) versus non-IMT in patients undergoing mechanical ventilation to improve the outcome of mechanical ventilation weaning time.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • invasive mechanical ventilation
  • patients hemodynamically stable
  • without use of vasoactive drugs

Exclusion

Exclusion Criteria:

  • spindle trauma
  • neuromuscular diseases
  • end-stage disease
  • pneumothorax
  • rib fracture
  • diaphragmatic injury
  • postoperative pulmonary surgeries
  • abdominal disease
  • morbidities that have repercussions on diaphragmatic contraction
  • mechanical ventilation with FiO2 > 60% and PEEP > 10 cm H2O

Study Design

Total Participants: 40
Treatment Group(s): 2
Primary Treatment: Inspiratory Muscle Training (IMT)
Phase:
Study Start date:
January 15, 2019
Estimated Completion Date:
December 31, 2023

Study Description

The study will consist of a randomized controlled clinical trial conducted at the Intensive Care Unit of the University Hospital of UNIVASF. Will be included individuals of both sexes, aged 18 years or older, who are on invasive mechanical ventilation and who obtain the Free and Informed Consent Form, signed by the responsible family member. Subjects will be randomized into two groups (training and control). The inspiratory (MIP), expiratory (MEP) and peak expiratory flow pressures will be evaluated. The training group will perform respiratory muscle training, using the Powerbreath equipment, with initial loading of 40% of MIP, 7 days a week, 2 times a day. Morbidities that have repercussions on diaphragmatic contraction and end-stage disease will be used as exclusion criteria. The sample data will be analyzed through the SPSS 22.0 program. The significance level of the study will be set at 5% (p <0.05).

Connect with a study center

  • Physical Education College

    Petrolina, Pernambuco 56304917
    Brazil

    Active - Recruiting

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