Effect of Panax Ginseng C.A. Mey Extract on Liver Function in Adults

Last updated: June 1, 2025
Sponsor: Pusan National University Yangsan Hospital
Overall Status: Active - Recruiting

Phase

N/A

Condition

Primary Biliary Cholangitis

Treatment

Placebo group

Panax Ginseng C.A. Mey Extract group

Clinical Study ID

NCT03775837
02-2018-031
  • Ages 19-75
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

The investigators conduct a randomized, double-blind, placebo-controlled study to investigate the effects of Panax Ginseng C.A. Mey Extract on liver function in adults for 8 weeks.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • ALT ranging from upper limit of reference to three times of upper limit

Exclusion

Exclusion Criteria:

  • Abnormal liver or renal function (i.e., serum aminotransferase activity > 3 times ofupper limit of reference range and serum creatinine concentrations > 1.2 mg/dL)

  • Diabetes (diagnosed clinically or fasting glucose level > 126 mg/dL)

  • History of viral hepatitis or cancer

  • Uncontrolled hypertension

  • History of serious cardiac disease such as angina or myocardial infarction

  • History of gastrectomy

  • History of medication for psychiatric disease

  • Administration of oriental medicine including herbs within the past 4 weeks

Study Design

Total Participants: 60
Treatment Group(s): 2
Primary Treatment: Placebo group
Phase:
Study Start date:
December 01, 2018
Estimated Completion Date:
December 31, 2025

Study Description

Previous studies have indicated that Panax Ginseng C.A. Mey Extract may have the ability to improve liver function. Therefore, the investigators conduct a randomized, double-blind, placebo-controlled study to investigate the effects of the Panax Ginseng C.A. Mey Extract on liver function in adults; the safety of the compound are also evaluate. The Investigators examine AST, ALT, GGT, and other metabolic parameters at baseline, as well as after 4 and 8 weeks of intervention. Sixty adults were administered either 600 mg of Panax Ginseng C.A. Mey Extract or a placebo each day for 8 weeks;

Connect with a study center

  • Integrated Research Institute for Natural Ingredients and Functional Foods

    Yangsan, 50612
    Korea, Republic of

    Active - Recruiting

Map preview placeholder

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.