REal World Data in LYmphoma and Survival in Adults

Last updated: June 25, 2021
Sponsor: Hospices Civils de Lyon
Overall Status: Active - Recruiting

Phase

N/A

Condition

Lymphoma

Marginal Zone Lymphoma

Hematologic Cancer

Treatment

N/A

Clinical Study ID

NCT03869619
69HCL18_0352
2018-A01332-53
  • Ages > 18
  • All Genders

Study Summary

REALYSA cohort is a population-based epidemiological platform in real-life for lymphomas designed to enrich prognostic data, by integrating together epidemiological, clinical and biological data.

REALYSA is a platform perfectly set up to

  • Study prognostic factors using integrated epidemiological and biological data (genetics), to better characterize the determinants of refractoriness and relapse in patients with lymphoma, to follow the growing number of survivors and describe median to long-term sequela, second cancer, quality of life (QoL)…

  • Document treatment effectiveness in real life and observance

  • Address socio-economical questions

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Signature of the consent form for participation in the REALYSA cohort
  • Aged over 18 at the time of inclusion
  • Diagnosed with lymphoma in the last 6 months (180 days)
  • Lymphoma subtype belonging to at least one of the 7 histological subtypes: diffuselarge B-cell lymphoma, follicular lymphoma, mantle cell lymphoma, marginal zonelymphoma, T-cell lymphoma, Hodgkin's lymphoma, Burkitt lymphoma

Exclusion

Exclusion Criteria:

  • Anti-lymphoma treatment already received (except pre-phase: typically corticosteroids,vincristine, cyclophosphamide, etoposide, alone or in combination)
  • Documented HIV infection
  • Any other lymphoma subtype not included in the list in Appendix 1. Of note, areexcluded:
  • Chronic lymphocytic leukemia/small lymphocytic lymphoma
  • Hairy cell leukemia and variant
  • Lymphoplasmacytic lymphoma
  • Waldenström macroglobulinemia
  • Primary DLBCL of the central nervous system (CNS)
  • T-cell large granular lymphocytic leukemia
  • Chronic lymphoproliferative disorder of NK cells
  • Mycosis fungoides
  • Sézary syndrome
  • Primary cutaneous T cell lymphomas (mainly diagnosed and treated bydermatologists)
  • Post-transplant lymphoproliferative disorders (PTLD)

Study Design

Total Participants: 6000
Study Start date:
November 14, 2018
Estimated Completion Date:
November 14, 2027

Connect with a study center

  • Unité d'Hématologie Clinique, CH D'ARRAS

    Arras, 62022
    France

    Active - Recruiting

  • Service d'Hématologie, CHU Jean Minjoz

    Besançon, 25030
    France

    Active - Recruiting

  • Institut Bergonié

    Bordeaux,
    France

    Active - Recruiting

  • Service d'Onco-radiolothérapie, Polyclinique Bordeaux Nord Aquitaine

    Bordeaux, 33300
    France

    Active - Recruiting

  • Centre Hospitalier Pierre Oudot

    Bourgoin-Jallieu, 38302
    France

    Active - Recruiting

  • Service d'Hématologie, Institut d'Hématologie de Basse Normandie

    Caen, 14000
    France

    Active - Recruiting

  • METROPOLE SAVOIE - SITE CHAMBERY, place Lucien Biset,

    Chambéry, 73000
    France

    Active - Recruiting

  • Service d'Hématologie Clinique et de Thérapie Cellulaire, Hôpital Estaing, CHU de Clermont-Ferrand

    Clermont-Ferrand, 63000
    France

    Active - Recruiting

  • Unité Hémopathies Lymphoïdes, Hôpital Henri Mondor

    Créteil, 94010
    France

    Active - Recruiting

  • CHU Francois MITTERRAND

    Dijon,
    France

    Active - Recruiting

  • Service Hématologie, Centre Hospitalier de Dunkerque

    Dunkerque, 59140
    France

    Active - Recruiting

  • Service Oncologie médicale, Groupe Hospitalier Mutualiste de Grenoble, Institut Daniel Hollard,

    Grenoble, 38028
    France

    Active - Recruiting

  • CHD Vendée

    La Roche-sur-Yon,
    France

    Active - Recruiting

  • Service d'Hématologie Clinique, Centre Hospitalier Universitaire Michallon

    La Tronche, 38700
    France

    Active - Recruiting

  • Clinique Victor Hugo

    Le Mans, 72000
    France

    Active - Recruiting

  • Centre hospitalier Libourne

    Libourne, 33500
    France

    Active - Recruiting

  • Service Oncologie médicale, HOPITAL SAINT VINCENT-DE-PAUL

    Lille, 59020
    France

    Active - Recruiting

  • Service des maladies du sang, Hôpital Claude Huriez, CHRU de Lille

    Lille, 59037
    France

    Active - Recruiting

  • Service Hématologie Clinique et Thérapie Cellulaire, CHU DE LIMOGES - HOPITAL DUPUYTREN,

    Limoges, 87042
    France

    Active - Recruiting

  • Département d'Hématologie et Oncologie, Centre Léon Bérard

    Lyon, 69008
    France

    Active - Recruiting

  • Département d'Hématologie Clinique, Hôpital Saint-Eloi,

    Montpellier, 34295
    France

    Active - Recruiting

  • Service Hématologie, GH REGION MULHOUSE ET SUD ALSACE - HOPITAL EMILE MULLER,

    Mulhouse, 68070
    France

    Active - Recruiting

  • Service d'Hématologie clinique, Centre Hospitalier Universitaire de Nantes

    Nantes, 44093
    France

    Active - Recruiting

  • Centre Hospitalier de Niort

    Niort, 79021
    France

    Active - Recruiting

  • Service Hématologie, Hôpital St Louis

    Paris, 75475
    France

    Active - Recruiting

  • CHU Haut-Lévêque

    Pessac,
    France

    Active - Recruiting

  • Centre Hospitalier Lyon Sud

    Pierre-Bénite,
    France

    Active - Recruiting

  • Service d'Hématologie et Thérapie Cellulaire, Centre Hospitalier Universitaire de Poitiers

    Poitiers, 86021
    France

    Active - Recruiting

  • Hématologie Clinique, CHU PONTCHAILLOU

    Rennes, 35033
    France

    Active - Recruiting

  • Service Hématologie, Centre Hospitalier de Roubaix - Hôpital Victor Provo

    Roubaix, 59056
    France

    Active - Recruiting

  • Service Hématologie, UNIVERSITE DE ROUEN, CENTRE HENRI BECQUEREL

    Rouen, 76038
    France

    Active - Recruiting

  • Service Hématologie, CH YVES LE FOLL

    Saint-Brieuc, 22027
    France

    Active - Recruiting

  • Service Hématologie, Institut Curie - Hôpital René HUGUENIN

    Saint-Cloud, 92210
    France

    Active - Recruiting

  • Département d'Hématologie Clinique et Thérapie Cellulaire, Institut de Cancérologie Lucien Neuwirth

    Saint-Priest-en-Jarez, 42270
    France

    Active - Recruiting

  • Hôpitaux Universitaires de Strasbourg

    Strasbourg,
    France

    Active - Recruiting

  • Institut Universitaire du Cancer

    Toulouse,
    France

    Active - Recruiting

  • Hématologie Clinique, CH DE BRETAGNE ATLANTIQUE

    Vannes, 56017
    France

    Active - Recruiting

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