CPAP, Nutrition & Exercise Against Sleep Apnea

Last updated: August 5, 2021
Sponsor: Raphael Heinzer
Overall Status: Active - Recruiting

Phase

N/A

Condition

Sleep Apnea Syndromes

Hypertriglyceridemia

Sleep Disorders

Treatment

N/A

Clinical Study ID

NCT03959280
2019-00586
  • Ages 18-75
  • All Genders

Study Summary

This study evaluates the addition of a comprehensive lifestyle program including dietary management and exercise to continuous positive airway pressure (CPAP) therapy in overweighted adults with obstructive sleep apnea. Half of the participants will receive CPAP therapy while the other half will have diet consultations, nordic walking sessions and CPAP.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patients newly diagnosed for obstructive sleep apnea and requiring CPAP therapy
  • BMI>25and≤40kg/m2
  • Low physical activity (< 150 min of MVPA per week)
  • IAH≥15
  • Able to give informed consent as documented by signature

Exclusion

Exclusion Criteria:

  • Patients already treated for OSA or another sleep disorder
  • Required use of supplemental oxygen
  • Active infection, malignancy or chronic inflammatory disorders
  • More than moderate alcohol use of > 14 drinks per week
  • Severe depression defined by a BDI > 30
  • Surgery within the previous 3 months
  • Known cardiac or pulmonary disease contraindicating exercise training
  • Patient with a bariatric surgery project or already operated
  • Pregnant or lactating women
  • Onset of a severe cardiac disease contraindicating exercise training
  • Inability to follow the procedures of the study, e.g. due to language problems,psychological disorders, dementia, peripheral functional limitation.

Study Design

Total Participants: 120
Study Start date:
August 21, 2019
Estimated Completion Date:
December 31, 2022

Study Description

While the specific impact of obstructive sleep apnea (OSA) on quality of life is well established, the impact of CPAP therapy on quality of life remains unclear. Yet, improving the quality of life of OSA patient is one of the main targets of treatment.

Both exercise and healthy diet are recommended in the management of overweight and obesity. This should improve quality of life as well as comorbidities associated with sleep apnea.

Connect with a study center

  • Centre Hospitalier Universitaire Saint-Etienne

    Saint-Étienne, 42055
    France

    Active - Recruiting

  • Centre Hospitalier Universitaire Vaudois

    Lausanne, 1011
    Switzerland

    Active - Recruiting

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