Evaluation of Extubation Criteria in Children With Upper Respiratory Infection (URI)

Last updated: November 27, 2024
Sponsor: Wake Forest University Health Sciences
Overall Status: Active - Recruiting

Phase

N/A

Condition

Respiratory Syncytial Virus (Rsv) Infection

Treatment

N/A

Clinical Study ID

NCT04155892
IRB00056059
  • Ages < 7
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

The investigators are currently completing a data collection to try to optimize pediatric patients' preoperative screening, in the setting of an upper respiratory infection.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • All study participants must be undergoing general anesthesia and surgery with anendotracheal tube

  • The URI group will be participants with a score of at least 3 on our pre-operativeURI survey, with planned airway instrumentation with an endotracheal tube (ETT) fortheir surgical procedure who are to be discharged same day or on postoperative day

  • The non URI group will be participants undergoing elective procedures with no URIsymptom or recent URI. Defined as no URI or "allergy" symptom within the past 6weeks and a score of 1 or less on the URI survey, with planned airwayinstrumentation with an ETT for their surgical procedure who are to be dischargedsame day or on postoperative day 1.

Exclusion

Exclusion Criteria:

  • History of home oxygen use or ventilator dependence,

  • Patients undergoing emergent procedures.

  • Patients with cyanotic congenital heart disease.

  • Patients receiving a surgical procedure where the duration of post procedure

  • admission is anticipated to be greater or equal to 2 postoperative days.

  • Patients undergoing anesthesia for imaging procedures alone.

  • Patients who are extubated deep intentionally.

  • Patients intended to be managed with supraglottic airway.

  • Patients undergoing total IV anaesthesia (TIVA).

Study Design

Total Participants: 760
Study Start date:
December 04, 2019
Estimated Completion Date:
April 30, 2025

Study Description

The objectives of this study are to evaluate various extubation criteria and their predictive value for successful extubation in non-cardiac surgical procedures. To evaluate the predictive value of room air oxygen and an original preoperative URI questionnaire in pediatric patients with URI or URI symptoms.

Connect with a study center

  • Wake Forest University Health Sciences

    Winston-Salem, North Carolina 27157
    United States

    Active - Recruiting

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