Prevalence of Hirsutism in Turkey: Data of The Dermatoendocrinology Study Group

Last updated: March 1, 2020
Sponsor: Istanbul Medeniyet University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Female Hormonal Deficiencies/abnormalities

Male Hormonal Deficiencies/abnormalities

Treatment

N/A

Clinical Study ID

NCT04292587
08122018
  • Ages 18-45
  • Female
  • Accepts Healthy Volunteers

Study Summary

Hirsutism is defined as the excessive presence of terminal hairs in the androgen-sensitive areas of the female body, and it is one of the frequent reasons for presenting to dermatology outpatient clinics. Hirsutism influences 5% to 10% of women around the world and leads to psychological problems depending on ethnic and socio-cultural factors. It also causes material burden including medicines, cosmetic products and epilation procedures.

The differences in the real prevalence of hirsutism in the Turkish population and the hirsutism prevalence and severity between the geographical regions of Turkey are not known. In this study, we aimed to determine the prevalence of hirsutism in women at the reproductive age within Turkey. The geographical regions of Turkey comprise seven regions and and all regions were included in this study. By considering the regions where ethnic differences were high including the east-west-south and north of our country, we aimed to find an answer to the question of whether there were differences in terms of the prevalence and severity of hirsutism among these regions. A comprehensive study aiming to determine the prevalence of hirsutism in Turkey has not been conducted.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Female patients aged between 18 and 45, who presented to the dermatology outpatientclinics for any reason

  • Not being in pregnancy and lactation period

  • Not applying permanent epilation

  • Not using temporary hair reduction methods in the last 4 weeks

  • Not using oral contraceptive, corticosteroid, cyclosporin or spironolactone in thelast 3 months

Exclusion

Exclusion Criteria:

  • Female patients below the age of 18, above 45 and men in any age group

  • Pregnant women and women in lactation period

  • Patients who had permanent epilation

  • Patients who had temporary hair reduction methods in the last 4 weeks

  • Patients taking oral contraceptive, corticosteroid, cyclosporin or spironolactone inthe last 3 months

Study Design

Total Participants: 5861
Study Start date:
February 03, 2020
Estimated Completion Date:
September 30, 2020

Study Description

Twenty-two provinces of Turkey's seven regions and 26 hospitals from these provinces will be included in the study. The number of samples was specified by the public health specialist on the 2018 census figures. The Turkish population consists of 80,810,525 people according to the data announced by the Turkish Statistical Institute in 2018. In order to determine the prevalence in Turkey, the sample size was calculated with a confidence interval of 99% and error margin of 1%, and the total number of individuals to be screened was designated as 5861. The number of patients to be screened via the clustering method weighted by regions was specified as 1800 for the Marmara Region, 750 for the Aegean Region, 744 for the Mediterranean Region, 568 for the Black Sea Region, 932 for the Central Anatolia Region, 434 for the Eastern Anatolia Region and 633 for the Southeastern Anatolia Region. The provinces that were thought to represent each region were selected via the cluster sampling method.

During the study period, female patients aged between 18 and 45, who present to dermatology outpatient clinics, will be examined clinically until the number of patients designated for each study center is reached, and the hirsutism level of the patients diagnosed with hirsutism will be determined by using the modified Ferriman-Gallwey (mFG) scoring system. In this system, hair growth in nine regions (upper lip, chin, chest, upper back, lower back, upper abdomen, lower abdomen, upper arms and thighs) is graded between 0 and 4. And nine regions are scored between 0 (no terminal hairs) and 4 (excessive presence of terminal hairs). The score above 8 is considered hirsutism. The hirsutism family history, body mass index, menstrual cycle pattern, concomitant disease status (diabetes, hyperlipidemia, hypertension, thyroid disease), history of medication causing body hair growth, the acne presence and severity, presence and severity of androgenic alopecia, presence of seborrhea, presence and localization of acanthosis nigricans, presence of acrochordon, presence of hidradenitis suppurativa, presence of galactorrhea, presence of virilization symptoms and presence of cushingoid symptoms of all the examined patients will be investigated and recorded.

Connect with a study center

  • Adana City Training and Research Hospital

    Adana, 01358
    Turkey

    Active - Recruiting

  • School of Medicine, Aksaray University

    Aksaray, 68000
    Turkey

    Active - Recruiting

  • School of Medicine, Ankara Yıldırım Beyazıt University

    Ankara, 06010
    Turkey

    Active - Recruiting

  • School of Medicine, Aydın Adnan Menderes University

    Aydın, 09100
    Turkey

    Active - Recruiting

  • Bitlis Tatvan State Hospital

    Bitlis, 13200
    Turkey

    Active - Recruiting

  • School of Medicine, Uludag University

    Bursa, 16285
    Turkey

    Active - Recruiting

  • University of Health Sciences, Gazi Yasargil Training and Research Hospital

    Diyarbakır, 21070
    Turkey

    Active - Recruiting

  • School of Medicine, Trakya University

    Edirne, 22030
    Turkey

    Active - Recruiting

  • School of Medicine, Eskisehir Osmangazi University

    Eskisehir, 26040
    Turkey

    Active - Recruiting

  • School of Medicine, Gaziantep University

    Gaziantep, 27310
    Turkey

    Active - Recruiting

  • School of Medicine, Süleyman Demirel University

    Isparta, 32260
    Turkey

    Active - Recruiting

  • Istanbul Medeniyet University, Goztepe Research and Training Hospital

    Istanbul, 34730
    Turkey

    Active - Recruiting

  • Marmara University Pendik Training and Research Hospital

    Istanbul, 34899
    Turkey

    Active - Recruiting

  • University of Health Sciences, Bakırköy Sadi Konuk Training and Research Hospital

    Istanbul, 34147
    Turkey

    Active - Recruiting

  • University of Health Sciences, Sultan 2. Abdulhamid Han Training and Research Hospital

    Istanbul, 34668
    Turkey

    Active - Recruiting

  • University of Health Sciences, Umraniye Training and Research Hospital

    Istanbul, 34764
    Turkey

    Active - Recruiting

  • School of Medicine,Izmir Katip Celebi University

    Izmir, 35620
    Turkey

    Active - Recruiting

  • School of Medicine,Kahramanmaras Sutcu Imam University

    Kahramanmaras, 46050
    Turkey

    Active - Recruiting

  • School of Medicine, Kocaeli University

    Kocaeli, 41001
    Turkey

    Active - Recruiting

  • Meram School of Medicine, Necmettin Erbakan University

    Konya, 42090
    Turkey

    Active - Recruiting

  • School of Medicine, Celal Bayar University

    Manisa, 45140
    Turkey

    Active - Recruiting

  • Sanlıurfa Training and Research Hospital

    Sanlıurfa, 63300
    Turkey

    Active - Recruiting

  • School of Medicine, Namık Kemal University

    Tekirdag, 59030
    Turkey

    Active - Recruiting

  • School of Medicine,Tokat Gaziosmanpasa University

    Tokat, 60030
    Turkey

    Active - Recruiting

  • School of Medicine,Karadeniz Technical University

    Trabzon, 61080
    Turkey

    Active - Recruiting

  • University of Health Sciences, Van Training and Research Hospital

    Van, 65100
    Turkey

    Active - Recruiting

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