Phase
Condition
Geographic Atrophy
Macular Degeneration
Treatment
RPESC-RPE-4W
Clinical Study ID
Ages > 55 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Clinical diagnosis of dry AMD.
Ability to understand and give informed consent.
Adult male or female >55 years of age.
Medically suitable to undergo vitrectomy and subretinal injection (>60% on Karnofskyscale).
Postmenopausal if female (expected to be common for the age limitation), or thefemale partner of a male subject unable to father children.
If male, willing to use barrier and spermicidal contraception during the study.
Exclusion
Exclusion Criteria:
Allergy or hypersensitivity to dilation drops or fluorescein.
Active major medical conditions limiting ability to participate in the study.
Active malignancy or treatment with chemotherapy.
Systemic immunosuppressant therapy within past six months.
History of toxoplasmosis, retinal histoplasmosis or tuberculosis.
Receipt of investigational product (IP) in a clinical trial within prior six months.
Any other medical condition, which, in the Investigator's judgment, will interferewith the subject's ability to comply with the protocol, compromises subject safety,or interferes with the interpretation of the study results.
Pregnant or nursing females.
Study Design
Study Description
Connect with a study center
University of Michigan Kellogg Eye Center
Ann Arbor, Michigan 48105
United StatesActive - Recruiting
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