Effect of Vitamin D on Ovulation Rate in Women With Polycystic Ovary Syndrome

Inclusion Criteria:

• Premenopausal

• Aged 18-40 years

• Irregular long menstrual cycles (>35 days)

• PCOS according to the Rotterdam criteria

• Agree for transvaginal ultrasound

Exclusion Criteria:

• Use of hormonal medication (including contraception) within 3 months prior to studyinclusion, except the use of a progestogen to induce withdrawal bleeding every 3months

• History of any medical condition or medications that may predispose to vitamin Dsensitivity, altered vitamin D metabolism and/ or hypercalcemia, including activetuberculosis or current therapy for tuberculosis, sarcoidosis, history of renal/ureteral stones, parathyroid disease, renal or liver failure or current use ofanti-convulsants

• Use of insulin-sensitizing drugs, lipid lowering drugs or anti-hypertensive

• Anticipated to use the above medications in the coming one year

• Known type 2 diabetes mellitus

• Refusal to join the study

• Abnormal blood calcium level

For those on supplements, we asked them to stop their own supplements.