Atrial Fibrillation in Active Cancer Patients

Last updated: August 8, 2024
Sponsor: University Hospital, Caen
Overall Status: Active - Recruiting

Phase

N/A

Condition

Cancer

Dysrhythmia

Chest Pain

Treatment

occurence of atrial fibrillation

Clinical Study ID

NCT04696081
Pharmaco122020
  • Ages > 18
  • All Genders

Study Summary

Atrial fibrillation is a common complication of both cancer and anticancer drugs but the consequences of such events remain poorly known and are not adressed in both phase III oncological trials and cardiological guidelines. The objective of this study is to create a prospective multicenter international registry of adult patients with an active cancer and experiencing atrial fibrillation to study major cardiovascular events occurrence during a 1 year follow-up.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • adult patients

  • outpatients or hospitalized patients

  • with a confirmed cancer (other than basal-cell or squamous-cell carcinoma of theskin, primary brain tumor, known intracerebral metastases, or acute leukemia) and anactive cancer (defined as cancer that had been diagnosed within the past 6 months orrecurrent locally advanced or metastatic cancer, for which anticancer treatment wasbeing given at the time of enrollment or during 6 months before enrollment)

  • at least 1 episode of atrial fibrillation (new onset AF occuring after cancerdiagnosis or history of paroxysmal of persistant AF prior to cancer diagnosis and anAF recurrence after cancer diagnosis)

  • in sinus rhythm at the time of cancer diagnosis

Exclusion

Exclusion Criteria:

  • patient with palliative cares or other conditions resulting in short term death (death expected in the month following atrial fibrillation occurrence)

  • history of long-standing persistant or permanent AF prior to cancer diagnosis

Study Design

Total Participants: 1000
Treatment Group(s): 1
Primary Treatment: occurence of atrial fibrillation
Phase:
Study Start date:
September 01, 2021
Estimated Completion Date:
January 01, 2026

Connect with a study center

  • Alexandre

    Caen, Normandy 14000
    France

    Active - Recruiting

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