The Efficacy of Endovascular Treatment in FPOD With TASC C and D Lesions

Inclusion Criteria:

1. Patients over 18 years old

2. Patients with Rutherford classification range from 3 to 6

3. If patients with both lower limbs meeting the inclusion criteria, both side of limbcan be selected for this study

4. The lower extremity artery needs to have a healthy runoff of no less than 10 cmabove the ankle

5. The guide wire should pass through the lesion of femoropopliteal artery, and furtherendovascular treatment is performed. In this study, we did not limit the methods ofthe guide wire passing through the target lesion

6. If the first-time endovascular treatment is failure, patients undergo endovasculartreatment successfully at the second time, the patients can still be enrolled

7. For patients with aortoiliac artery lesions, they can be enrolled after thesuccessful reconstruction of aortoiliac artery

8. Informed consent signed by patients

Exclusion Criteria:

1. Patients who are unwilling or refuse to sign the informed consent form

2. Patients with acute and subacute lower extremity arterial thrombosis or arterialembolism

3. Patients with thromboangiitis obliterans

4. Patients with failure of endovascular treatment, and transferred to bypass surgery

5. Patients who underwent surgical atherectomy for common femoral artery occlusivelesions

6. Patients with known allergy to heparin, low molecular weight heparin and contrastagents

7. Patients who have been enrolled in other clinical trials in the past 3 months

8. Women during pregnancy and lactation

9. Patients with other diseases that may lead to difficulties in the trial orsignificantly shorten the life expectancy (< 3 years), such as tumors, severe liverdisease, cardiac insufficiency