Methodology for Developing an Occlusal Appliance With CBD Active Carrier

Phase

2/3

Condition

Oral Facial Pain

Muscle Pain

Progressive Supranuclear Palsy

Treatment

N/A

Clinical Study ID

NCT04775030

CBD-OCC-APP

Ages > 18
All Genders
Accepts Healthy Volunteers

Study Summary

Evaluation of the efficacy of the occlusal appliance with active cannabidiol (CBD) molecules in TMD patients

Eligibility Criteria

Inclusion

Inclusion Criteria:

patient agreement to take part in the study
RDC/TMD group Ia and Ib
Bruxism Index> 3 ( Brux-off polysomnography)

Exclusion

Exclusion Criteria:

CBD allergy/hypersensitivity/ addiction
Therapy with analgesic drugs
Therapy with drugs affecting muscle function
Fixed or removable dental prosthesis
Ongoing orthodontic treatment
Other general disorders affecting muscle tension

Study Design

January 01, 2021

January 01, 2023

Study Description

Occlusal appliance therapies are used in TMD patients. In this research the active CBD molecules will be released from the occlusal appliance during nighttime, in population of patients suffering from TMD. The effectiveness of the myorelaxation (sEMG of mastcatory muscles activity) and analgesic effect( VAS analysis) of occlusal appliance with the CBD molecules will be compared to the traditional acrylic-resin material used so far for occlusal appliance manufacture. The aim of the research is the evaluation of the innovative material effectiveness, used for the production of the occlusal appliance.

Connect with a study center

Department of TMD Silesian Medical University
Zabrze, 41-800
Poland
Active - Recruiting

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