Patisiran-Lipid Nanoparticle (LNP) Pregnancy Surveillance Program

Last updated: February 13, 2026
Sponsor: Alnylam Pharmaceuticals
Overall Status: Active - Recruiting

Phase

N/A

Condition

Neuropathy

Nerve Injury

Amyloidosis

Treatment

N/A

Clinical Study ID

NCT05040373
ALN-TTR02-010
  • Female

Study Summary

The purpose of this study is to collect and evaluate pregnancy outcomes, pregnancy complications, and fetal/neonatal/infant outcomes in women exposed to patisiran-LNP.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Documentation that the patient was exposed to patisiran-LNP at any point startingfrom 12 weeks before LMP or at any point during pregnancy

Exclusion

Exclusion Criteria:

  • There are no exclusion criteria for participation in this program.

Study Design

Total Participants: 10
Study Start date:
August 01, 2020
Estimated Completion Date:
October 12, 2030

Connect with a study center

  • Clinical Trial Site

    Nantes,
    France

    Site Not Available

  • Clinical Trial Site

    Nantes 2990969,
    France

    Active - Recruiting

  • Clinical Trial Site

    Münster,
    Germany

    Site Not Available

  • Clinical Trial Site

    Münster 2867543,
    Germany

    Active - Recruiting

  • Clinical Trial Site

    Pavia,
    Italy

    Site Not Available

  • Clinical Trial Site

    Pavia 3171366,
    Italy

    Active - Recruiting

  • Clinical Trial Site

    Groningen,
    Netherlands

    Site Not Available

  • Clinical Trial Site

    Groningen 2755251,
    Netherlands

    Active - Recruiting

  • Clinical Trial Site

    Lisboa,
    Portugal

    Site Not Available

  • Clinical Trial Site

    Lisbon 2267057,
    Portugal

    Active - Recruiting

  • Clinical Trial Site

    Madrid,
    Spain

    Site Not Available

  • Clinical Trial Site

    Madrid 3117735,
    Spain

    Active - Recruiting

  • Clinical Trial Site

    Iowa City, Iowa 52242
    United States

    Site Not Available

  • Clinical Trial Site

    Iowa City 4862034, Iowa 4862182 52242
    United States

    Active - Recruiting

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