Nerve Composition of Human Lumbar Dorsal Primary Rami and Its Medial Branch

Last updated: December 18, 2024
Sponsor: University of Aberdeen
Overall Status: Active - Recruiting

Phase

N/A

Condition

Osteoarthritis

Nerve Injury

Treatment

Histology

Spinal surgery

Clinical Study ID

NCT05091112
1-076-21
  • Ages > 18
  • All Genders

Study Summary

The purpose of the study is to understand the composition of the nerves supplying the facet joints in low back.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Be aged 18 or over

  • be able to give informed consent

  • scheduled to undergo lumbar spinal surgery

Exclusion

Exclusion Criteria:

  • Children under 18 years old

  • Vulnerable adults

  • Adults with incapacity

  • Inability to provide informed consent

  • History of previous spinal surgery

  • history of previous RF ablation for low back pain

  • has COVID-19 or displaying symptoms of COVID-19

Study Design

Total Participants: 20
Treatment Group(s): 2
Primary Treatment: Histology
Phase:
Study Start date:
March 08, 2022
Estimated Completion Date:
December 31, 2024

Study Description

After written informed consent, the nerves supplying the facet joints - lumbar dorsal rami and its medial branches, will be harvested when they are exposed during spinal surgery. These nerves will be fixed, washed and further dissected to enable smaller sections. The cut section will be stained and subjected to analysis of overall cross-sectional area and presence of connective tissue sheaths under light microscope.

Connect with a study center

  • Woodend Hospital

    Aberdeen, Scotland AB15 6XS
    United Kingdom

    Active - Recruiting

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