Ventilator Strategies in ICU Patients With COVID-19 - a National-wide Retrospective Observational Study.

Last updated: November 3, 2021
Sponsor: University of Southern Denmark
Overall Status: Active - Recruiting

Phase

N/A

Condition

Covid-19

Treatment

N/A

Clinical Study ID

NCT05102630
2020-C 19-29-10-21
  • All Genders

Study Summary

Mechanical ventilation is likely lifesaving in patients with coronavirus disease 2019 (COVID-19) but may also result in adverse events. Only few studies describe the strategies used and adverse effect of mechanical ventilation in an unselected population of ICU patients with COVID-19.

This study is designed to be a retrospective study focusing on all mechanical ventilated ICU patients with COVID-19 included in the national Danish COVID ICU database between 10.03.2020

  • 02.04.2021 i.e. a total of 1,193 patients. The investigators will register the use of the core interventions around mechanical ventilation and its potential adverse event, including barotrauma and prolonged ventilation.

This study will provide important data on the ventilation strategies used and its potential adverse events in unselected ICU patients with COVID-19 and thereby inform clinicians, patients, policy-makers, and future research in this area.

Eligibility Criteria

Inclusion

Inclusion Criteria: All mechanical ventilated patients registered in the national Danish COVID ICU databasebetween 10.03.2020 - 02.04.2021 i.e.

  1. Admitted to an ICU in Denmark
  2. Laboratory-confirmed SARS-CoV-2 infection
  3. Use of invasive mechanical ventilation (ventilation via a cuffed endotracheal tube) atany time during the ICU stay

Exclusion

Exclusion Criteria: None

Study Design

Total Participants: 1193
Study Start date:
June 01, 2021
Estimated Completion Date:
April 30, 2022

Connect with a study center

  • Department of Anaesthesiology and Intensive Care Medicine, Aalborg University Hospital

    Aalborg, 9000
    Denmark

    Active - Recruiting

  • Department of Anesthesiology and Intensive Care, Kolding Hospital

    Kolding, 6000
    Denmark

    Active - Recruiting

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