Postoperative Hypoxia and Body Position

Last updated: March 28, 2023
Sponsor: Umeå University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Abdominal Surgery

Treatment

N/A

Clinical Study ID

NCT05246605
2021-04457
  • Ages > 18
  • All Genders

Study Summary

The study aims at investigate whether the oxygen partial pressure is improved in the prone position postoperative after abdominal surgery. Included are 50 adults operated with abdominal surgery. The Intervention is turning from supine to prone position and then back to supine position while measuring whether an improvement occurs in oxygen saturation and oxygen partial pressure, or not.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Being operated within 2 in the abdomen because of upper gastrointestinal surgery,colorectal surgery, urological surgery or emergency surgery
  • Must be able to turn from supine position to prone position in the bed

Exclusion

Exclusion Criteria:

  • Esophageal surgery, Abdominal vessel surgery.
  • Decline participation.

Study Design

Total Participants: 34
Study Start date:
March 16, 2022
Estimated Completion Date:
December 01, 2023

Study Description

Postoperative hypoxia complicates 30% - 50% of abdominal surgeries. The cause of postoperative restrictive lung function and hypoxia is unknown. Previous studies report that oxygen partial pressure decreases by an average of 2 kPa after abdominal surgery, while carbon dioxide partial pressure is unchanged and vital capacity decreases by 35%. Patients are operated and treated in the post anesthesia care unit in the supine position. The study aims at investigate whether the oxygen partial pressure is improved in the prone position postoperative after abdominal surgery or not.

Inclusion: 50 adults operated with abdominal surgery. Exclusion: Esophageal surgery, Abdominal vessel surgery. Decline participation. Intervention: turning from supine to prone position and then back to supine position again.

Primary outcome: Change in oxygen saturation and oxygen partial pressure. Secondary outcome: Change in carbondioxide partial pressure Procedures: Partial blood gas is taken before surgery. On the day of surgery or the day after: starting in supine position with continuous measurements of oxygen saturation from pulse oximetry, transcutaneous carbon-dioxide partial pressure and blood gas. Then turning to prone position and then back to supine position.

Connect with a study center

  • Dept of Surgery, University hospital

    Umea, Vasterbotten 90185
    Sweden

    Active - Recruiting

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.