Living Donor Liver Transplant for Unresectable Colorectal Liver Metastases

Last updated: May 22, 2024
Sponsor: University of Rochester
Overall Status: Active - Recruiting

Phase

N/A

Condition

Neoplasm Metastasis

Treatment

Liver transplantation

Clinical Study ID

NCT05248581
STUDY00004076
  • Ages > 18
  • All Genders

Study Summary

The goal of this study is to create a data registry to capture clinical, pathologic, and molecular data/outcomes for patients with metastatic colorectal cancer who undergo live donor liver transplantation.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age ≥ 18

  • Non-amenable to curative hepatic resection as defined by FLR <30%

  • Histologically confirmed adenocarcinoma of the colon or rectum

  • Candidate for LDLT for colorectal liver metastasis per the University of Rochesterliver transplant program

Exclusion

Exclusion Criteria:

  • Not a candidate of the LDLT liver transplant protocol for treatment of colorectalliver metastasis.

  • Unwilling to consent

Study Design

Total Participants: 25
Treatment Group(s): 1
Primary Treatment: Liver transplantation
Phase:
Study Start date:
August 16, 2019
Estimated Completion Date:
August 01, 2027

Study Description

The goal of this study is to create a data registry to capture clinical, pathologic, and molecular data/outcomes for patients with metastatic colorectal cancer who undergo live donor liver transplantation.

Our primary outcome of interest was the OS and recurrence-free survival (RFS) of patients who underwent LDLT at our center.

Connect with a study center

  • University of Rochester Medical Center

    Rochester, New York 14642
    United States

    Active - Recruiting

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