Met Non Small Cell Cancer Registry (MOMENT)

Last updated: March 4, 2026
Sponsor: EMD Serono Research & Development Institute, Inc.
Overall Status: Active - Recruiting

Phase

N/A

Condition

Neoplasms

Cancer

Treatment

N/A

Clinical Study ID

NCT05376891
MS200095_0050
  • All Genders

Study Summary

The purpose of this multi-national disease registry is to collect prospectively (with longitudinal follow-up) high-quality, standardized, and contemporaneous data to capture changes in the non-small cell lung cancer (NSCLC) treatment landscape and outcomes over time.

The registry will capture data on participants; demographic, clinical characteristics (including biomarker data), treatment patterns, and effectiveness and safety outcomes for advanced NSCLC with mesenchymal-epithelial transition exon 14 (METex14) participants treated with systemic therapy.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Participants who signed ICF

  • Participants with advanced stage (stages IIIB-IV) NSCLC (all histologies) andConfirmed METex14 skipping alterations (by valid assay)

  • Participants who are starting or are already being treated with systemic therapy

Exclusion

Exclusion Criteria:

  • Participants who are enrolled in a clinical trial

Study Design

Total Participants: 700
Study Start date:
October 04, 2022
Estimated Completion Date:
April 28, 2028

Study Description

This is a disease registry, which is an organized system using non-interventional methods to collect data on a patient population defined by a particular disease, exposure, or condition, and which is followed over time. Non-interventional means that after participants enrollment, participants will be treated according to the routine clinical treatment decision by the physician. The registry will not impose any treatment or procedure for participants.

Connect with a study center

  • Klinikum Klagenfurt Am Woerthersee

    Klagenfurt,
    Austria

    Active - Recruiting

  • Klinikum Klagenfurt Am Woerthersee

    Klagenfurt 2774326,
    Austria

    Site Not Available

  • Klinikum Klagenfurt Am Woerthersee

    Klagenfurt am Wörthersee,
    Austria

    Site Not Available

  • Klinik Floridsdorf

    Vienna,
    Austria

    Active - Recruiting

  • Klinik Floridsdorf

    Vienna 2761369,
    Austria

    Site Not Available

  • Klinik Floridsdorf

    Wien,
    Austria

    Site Not Available

  • AZ Delta

    Roeselare,
    Belgium

    Active - Recruiting

  • AZ Delta

    Roeselare 2787889,
    Belgium

    Site Not Available

  • AZ Nikolaas

    Sint-Niklaas,
    Belgium

    Active - Recruiting

  • AZ Nikolaas

    Sint-Niklaas 2786578,
    Belgium

    Site Not Available

  • CHU UCL Namur asbl - Site Godinne

    Yvoir,
    Belgium

    Site Not Available

  • Ottawa Hospital

    Ottawa,
    Canada

    Site Not Available

  • Ottawa Hospital General Campus

    Ottawa,
    Canada

    Active - Recruiting

  • Ottawa Hospital General Campus

    Ottawa 6094817,
    Canada

    Site Not Available

  • OCREB

    Toronto,
    Canada

    Site Not Available

  • Princess Margaret Cancer Centre

    Toronto,
    Canada

    Active - Recruiting

  • Princess Margaret Cancer Centre

    Toronto 6167865,
    Canada

    Site Not Available

  • FN Olomouc

    Olomouc,
    Czechia

    Active - Recruiting

  • FN Olomouc

    Olomouc 3069011,
    Czechia

    Site Not Available

  • University Hospital Na Bulovce

    Prague,
    Czechia

    Active - Recruiting

  • University Hospital Na Bulovce

    Prague 3067696,
    Czechia

    Site Not Available

  • University Hospital Na Bulovce

    Praha 8,
    Czechia

    Site Not Available

  • University Hospital of Tampere

    Tampere,
    Finland

    Site Not Available

  • University Hospital of Tampere

    Tampere 634963,
    Finland

    Site Not Available

  • Turun Yliopistollinen Keskussairaala

    Turku,
    Finland

    Site Not Available

  • Turun Yliopistollinen Keskussairaala

    Turku 633679,
    Finland

    Site Not Available

  • Centre Hospitalier de Cholet

    Cholet,
    France

    Active - Recruiting

  • Centre Hospitalier de Cholet

    Cholet 3025053,
    France

    Site Not Available

  • CHRU Lille

    Lille,
    France

    Active - Recruiting

  • CHRU Lille

    Lille 2998324,
    France

    Site Not Available

  • CHRU Lille

    Lille cedex,
    France

    Site Not Available

  • Hôpital du Scorff

    Lorient,
    France

    Active - Recruiting

  • Hôpital du Scorff

    Lorient 2997577,
    France

    Site Not Available

  • Centre Leon Berard

    Lyon,
    France

    Active - Recruiting

  • Centre Leon Berard

    Lyon 2996944,
    France

    Site Not Available

  • Centre Leon Berard

    Lyon Cedex 08,
    France

    Site Not Available

  • Hospital Tenon & University Paris 6

    Paris,
    France

    Active - Recruiting

  • Institut Curie

    Paris,
    France

    Site Not Available

  • Institut Curie - Centre de Lutte Contre le Cancer (CLCC)

    Paris,
    France

    Active - Recruiting

  • Hospital Tenon & University Paris 6

    Paris 2988507,
    France

    Active - Recruiting

  • Institut Curie - Centre de Lutte Contre le Cancer (CLCC)

    Paris 2988507,
    France

    Site Not Available

  • Institut Curie - Centre de Lutte Contre le Cancer (CLCC)

    Paris Cedex 05,
    France

    Site Not Available

  • CHU de Toulouse Hopital Larrey

    Toulouse,
    France

    Active - Recruiting

  • Hôpital Larrey

    Toulouse,
    France

    Site Not Available

  • CHU de Toulouse Hopital Larrey

    Toulouse 2972315,
    France

    Site Not Available

  • Klinikum Chemnitz GmbH

    Chemnitz,
    Germany

    Active - Recruiting

  • Klinikum Chemnitz GmbH

    Chemnitz 2940132,
    Germany

    Site Not Available

  • Research Site

    Darmstadt,
    Germany

    Site Not Available

  • KKH Grosshansdorf GmbH

    Grosshansdorf,
    Germany

    Site Not Available

  • LungenClinic Grosshansdorf GmbH

    Grosshansdorf,
    Germany

    Site Not Available

  • KKH Grosshansdorf GmbH

    Großhansdorf,
    Germany

    Active - Recruiting

  • KKH Grosshansdorf GmbH

    Großhansdorf 2915556,
    Germany

    Site Not Available

  • Thoraxklinik-Heidelberg gGmbH

    Heidelberg,
    Germany

    Active - Recruiting

  • Thoraxklinik-Heidelberg gGmbH

    Heidelberg 2907911,
    Germany

    Site Not Available

  • Klinik Löwenstein GmbH

    Löwenstein,
    Germany

    Active - Recruiting

  • Klinik Löwenstein GmbH

    Löwenstein 2875656,
    Germany

    Site Not Available

  • Haemek Medical Center

    Afula,
    Israel

    Active - Recruiting

  • Haemek Medical Center

    Afula 295740,
    Israel

    Site Not Available

  • Assuta Ashdod Institutional Review Board

    Ashdod,
    Israel

    Site Not Available

  • Assuta Ashdod Medical Center

    Ashdod,
    Israel

    Site Not Available

  • Assuta Ashdod Medical Center

    Ashdod 295629,
    Israel

    Site Not Available

  • Bnai Zion Medical Center

    Haifa,
    Israel

    Site Not Available

  • Bnai Zion Medical Center EC

    Haifa,
    Israel

    Site Not Available

  • Bnei-Zion Medical Center

    Haifa,
    Israel

    Active - Recruiting

  • Carmel Medical Center

    Haifa,
    Israel

    Active - Recruiting

  • Institutional Helsinki Committee, The Lady Davis Carmel Medical Center

    Haifa,
    Israel

    Site Not Available

  • Rambam Medical Center - PPDS

    Haifa,
    Israel

    Active - Recruiting

  • Rambam Medical Center EC

    Haifa,
    Israel

    Site Not Available

  • Bnei-Zion Medical Center

    Haifa 294801,
    Israel

    Site Not Available

  • Carmel Medical Center

    Haifa 294801,
    Israel

    Active - Recruiting

  • Rambam Medical Center - PPDS

    Haifa 294801,
    Israel

    Active - Recruiting

  • Shaare Zedek Medical Center

    Jerusalem,
    Israel

    Active - Recruiting

  • Shaare Zedek Medical Center EC

    Jerusalem,
    Israel

    Site Not Available

  • Shaare Zedek Medical Center

    Jerusalem 281184,
    Israel

    Site Not Available

  • Rabin Medical Center Oncology Beilinson Campus

    Petach Tikva,
    Israel

    Site Not Available

  • Rabin Medical Center Oncology Beilinson Campus

    Petah Tikva,
    Israel

    Active - Recruiting

  • Rabin Medical Center Oncology Beilinson Campus

    Petah Tikva 293918,
    Israel

    Site Not Available

  • Chaim Sheba Medical Center

    Ramat Gan,
    Israel

    Active - Recruiting

  • Sheba Medical Center - PPDS

    Ramat Gan,
    Israel

    Site Not Available

  • The Chaim Sheba Medical Center EC

    Ramat Gan,
    Israel

    Site Not Available

  • Chaim Sheba Medical Center

    Ramat Gan 293788,
    Israel

    Site Not Available

  • Tel Aviv Sourasky EC

    Tel Aviv,
    Israel

    Site Not Available

  • Tel Aviv Sourasky Medical Center

    Tel Aviv,
    Israel

    Active - Recruiting

  • Tel Aviv Sourasky Medical Center

    Tel Aviv 293397,
    Israel

    Site Not Available

  • Tel Aviv Sourasky Medical Center PPDS

    Tel Aviv-Yafo,
    Israel

    Site Not Available

  • Istituto Europeo di Oncologia

    Milan,
    Italy

    Active - Recruiting

  • Istituto Nazionale Dei Tumori

    Milan,
    Italy

    Active - Recruiting

  • Istituto Europeo di Oncologia

    Milan 6951411,
    Italy

    Site Not Available

  • Istituto Nazionale Dei Tumori

    Milan 6951411,
    Italy

    Active - Recruiting

  • Istituto Europeo Di Oncologia

    Milano,
    Italy

    Site Not Available

  • Istituto Europeo di Oncologia

    Milano,
    Italy

    Active - Recruiting

  • Istituto Nazionale Dei Tumori

    Milano,
    Italy

    Site Not Available

  • AOU dell'Università degli Studi della Campania Luigi Vanvitelli

    Napoli,
    Italy

    Active - Recruiting

  • AOU dell'Università degli Studi della Campania Luigi Vanvitelli

    Napoli 9031661,
    Italy

    Site Not Available

  • Azienda Sanitaria Ospedaliera S Luigi Gonzaga

    Orbassano,
    Italy

    Site Not Available

  • Azienda Sanitaria Ospedaliera S Luigi Gonzaga

    Orbassano (TO),
    Italy

    Site Not Available

  • Istituto Nazionale Tumori Regina Elena

    Roma,
    Italy

    Site Not Available

  • I.F.O. Istituto Nazionale Tumori Regina Elena IRCCS

    Rome,
    Italy

    Active - Recruiting

  • I.F.O. Istituto Nazionale Tumori Regina Elena IRCCS

    Rome 3169070,
    Italy

    Site Not Available

  • Azienda Sanitaria Ospedaliera S Luigi Gonzaga

    Torino,
    Italy

    Active - Recruiting

  • Azienda Sanitaria Ospedaliera S Luigi Gonzaga

    Torino 8980539,
    Italy

    Site Not Available

  • Ospedale di Circolo

    Varese,
    Italy

    Active - Recruiting

  • Ospedale di Circolo

    Varese 3164699,
    Italy

    Site Not Available

  • VU Medisch Centrum

    Amsterdam,
    Netherlands

    Active - Recruiting

  • VU Medisch Centrum

    Amsterdam 2759794,
    Netherlands

    Site Not Available

  • Universitair Medisch Centrum Groningen

    Groningen,
    Netherlands

    Site Not Available

  • Universitair Medisch Centrum Groningen - Department of Medical Oncology

    Groningen,
    Netherlands

    Active - Recruiting

  • Universitair Medisch Centrum Groningen - Department of Medical Oncology

    Groningen 2755251,
    Netherlands

    Site Not Available

  • Leiden University Medical Center

    Leiden,
    Netherlands

    Active - Recruiting

  • Leiden University Medical Center

    Leiden 2751773,
    Netherlands

    Site Not Available

  • Centro Hospitalar de Lisboa Norte, EPE - Hospital de Santa Maria

    Lisboa,
    Portugal

    Active - Recruiting

  • Instituto Português de Oncologia de Lisboa Francisco Gentil, E.P.E.

    Lisboa,
    Portugal

    Site Not Available

  • Centro Hospitalar de Lisboa Norte, EPE - Hospital de Santa Maria

    Lisbon,
    Portugal

    Active - Recruiting

  • Centro Hospitalar de Lisboa Norte, EPE - Hospital de Santa Maria

    Lisbon 2267057,
    Portugal

    Site Not Available

  • Centro Hospitalar do Porto

    Porto,
    Portugal

    Site Not Available

  • Centro Hospitalar do Porto E.P.E. Hospital de Santo António

    Porto,
    Portugal

    Active - Recruiting

  • Centro Hospitalar do Porto E.P.E. Hospital de Santo António

    Porto 2735943,
    Portugal

    Site Not Available

  • Instituto Portugues de Oncologia Do Porto Francisco Gentil Epe - PPDS

    Porto Covo,
    Portugal

    Active - Recruiting

  • Instituto Portugues de Oncologia Do Porto Francisco Gentil Epe - PPDS

    Porto Covo 2264442,
    Portugal

    Site Not Available

  • Clinica Tres Torres

    Barcelona,
    Spain

    Active - Recruiting

  • Institut Universitari Dexeus-Quiron - Servei d oncologia medica - Institut Oncologic Dr. Rosell

    Barcelona,
    Spain

    Terminated

  • Clinica Tres Torres

    Barcelona 3128760,
    Spain

    Active - Recruiting

  • Institut Universitari Dexeus-Quiron - Servei d oncologia medica - Institut Oncologic Dr. Rosell

    Barcelona 3128760,
    Spain

    Site Not Available

  • Complejo Hospitalario Universitario Insular-Materno Infantil

    Las Palmas de Gran Canaria,
    Spain

    Terminated

  • Complejo Hospitalario Universitario Insular-Materno Infantil

    Las Palmas de Gran Canaria 2515270,
    Spain

    Site Not Available

  • Centro Integral Oncologico Clara Campa

    Madrid,
    Spain

    Active - Recruiting

  • Centro Oncologico MD Anderson

    Madrid,
    Spain

    Terminated

  • Centro Integral Oncologico Clara Campa

    Madrid 3117735,
    Spain

    Active - Recruiting

  • Centro Oncologico MD Anderson

    Madrid 3117735,
    Spain

    Site Not Available

  • Hospital Regional Universitario de Malaga - Hospital General

    Malaga,
    Spain

    Site Not Available

  • Hospital Regional Universitario de Malaga - Hospital General

    Málaga,
    Spain

    Active - Recruiting

  • Hospital Regional Universitario de Malaga - Hospital General

    Málaga 2514256,
    Spain

    Site Not Available

  • Hospidal Universitario Ntra. Sra. De Valme

    Sevilla,
    Spain

    Site Not Available

  • Hospital Universitario Virgen Macarena

    Sevilla,
    Spain

    Active - Recruiting

  • Hospidal Universitario Ntra. Sra. De Valme

    Seville,
    Spain

    Active - Recruiting

  • Hospital Universitario Virgen Macarena

    Seville,
    Spain

    Active - Recruiting

  • Hospidal Universitario Ntra. Sra. De Valme

    Seville 2510911,
    Spain

    Site Not Available

  • Hospital Universitario Virgen Macarena

    Seville 2510911,
    Spain

    Active - Recruiting

  • Hospital Universitari i Politecnic La Fe de Valencia

    Valencia,
    Spain

    Active - Recruiting

  • Hospital Universitari i Politecnic La Fe de Valencia

    Valencia 2509954,
    Spain

    Site Not Available

  • Complejo Hospitalario Universitario Insular-Materno Infantil

    las Palmas de Gran Canaria,
    Spain

    Site Not Available

  • Universitetssjukhuset i Linköping

    Linköping,
    Sweden

    Active - Recruiting

  • Universitetssjukhuset i Linköping

    Linköping 2694762,
    Sweden

    Site Not Available

  • Huddersfield Royal Infirmary

    Huddersfield, West Yorkshire HD3 3EA
    United Kingdom

    Site Not Available

  • Bedford General Hospital

    Bedford,
    United Kingdom

    Active - Recruiting

  • Bedford General Hospital

    Bedford 2656046,
    United Kingdom

    Site Not Available

  • Birmingham Heartlands Hospital

    Birmingham,
    United Kingdom

    Terminated

  • Queen Elizabeth Hospital Birmingham

    Birmingham,
    United Kingdom

    Site Not Available

  • Birmingham Heartlands Hospital

    Birmingham 2655603,
    United Kingdom

    Site Not Available

  • Royal Bournemouth Hospital

    Bournemouth,
    United Kingdom

    Active - Recruiting

  • Royal Bournemouth Hospital

    Bournemouth 2655095,
    United Kingdom

    Site Not Available

  • The Royal Marsden Hospital

    Chelsea,
    United Kingdom

    Active - Recruiting

  • The Royal Marsden Hospital

    Chelsea 2653265,
    United Kingdom

    Site Not Available

  • Royal Surrey County Hospital

    Guildford,
    United Kingdom

    Site Not Available

  • Royal Surrey County Hospital

    Guildford 2647793,
    United Kingdom

    Site Not Available

  • Northwick Park Hospital

    Harrow,
    United Kingdom

    Active - Recruiting

  • Northwick Park Hospital

    Harrow 2647425,
    United Kingdom

    Site Not Available

  • Clatterbridge Cancer Centre - Liverpool

    Liverpool,
    United Kingdom

    Active - Recruiting

  • Clatterbridge Cancer Centre - Liverpool

    Liverpool 2644210,
    United Kingdom

    Site Not Available

  • Charing Cross Hospital

    London,
    United Kingdom

    Active - Recruiting

  • Guy's Cancer Centre

    London, SE1 9RT
    United Kingdom

    Site Not Available

  • Charing Cross Hospital

    London 2643743,
    United Kingdom

    Site Not Available

  • Preston Hospital

    Preston,
    United Kingdom

    Active - Recruiting

  • Preston Hospital

    Preston 2639912,
    United Kingdom

    Site Not Available

  • Good Hope Hospital

    Sutton Coldfield,
    United Kingdom

    Site Not Available

  • Holy Cross Health

    Fort Lauderdale, Florida 33308-4603
    United States

    Active - Recruiting

  • Holy Cross Health

    Fort Lauderdale 4155966, Florida 4155751 33308-4603
    United States

    Site Not Available

  • Research Site

    Rockland, Massachusetts 02370
    United States

    Site Not Available

  • The Ohio State University Wexner Medical Center

    Columbus, Ohio 43221
    United States

    Active - Recruiting

  • The Ohio State University Wexner Medical Center

    Columbus 4509177, Ohio 5165418 43221
    United States

    Site Not Available

  • Vanderbilt University Medical Center

    Nashville, Tennessee 37212
    United States

    Site Not Available

  • Vanderbilt University Medical Center

    Nashville 4644585, Tennessee 4662168 37212
    United States

    Site Not Available

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