Met Non Small Cell Cancer Registry (MOMENT)

Last updated: March 18, 2025
Sponsor: EMD Serono Research & Development Institute, Inc.
Overall Status: Active - Recruiting

Phase

N/A

Condition

Cancer

Treatment

N/A

Clinical Study ID

NCT05376891
MS200095_0050
  • All Genders

Study Summary

The purpose of this multi-national disease registry is to collect prospectively (with longitudinal follow-up) high-quality, standardized, and contemporaneous data to capture changes in the non-small cell lung cancer (NSCLC) treatment landscape and outcomes over time.

The registry will capture data on participants; demographic, clinical characteristics (including biomarker data), treatment patterns, and effectiveness and safety outcomes for advanced NSCLC with mesenchymal-epithelial transition exon 14 (METex14) participants treated with systemic therapy.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Participants who signed ICF

  • Participants with advanced stage (stages IIIB-IV) NSCLC (all histologies) andConfirmed METex14 skipping alterations (by valid assay)

  • Participants who are starting or are already being treated with systemic therapy

Exclusion

Exclusion Criteria:

  • Participants who are enrolled in a clinical trial

Study Design

Total Participants: 700
Study Start date:
October 04, 2022
Estimated Completion Date:
March 31, 2027

Study Description

This is a disease registry, which is an organized system using non-interventional methods to collect data on a patient population defined by a particular disease, exposure, or condition, and which is followed over time. Non-interventional means that after participants enrollment, participants will be treated according to the routine clinical treatment decision by the physician. The registry will not impose any treatment or procedure for participants.

Connect with a study center

  • Klinikum Klagenfurt Am Woerthersee

    Klagenfurt am Wörthersee,
    Austria

    Active - Recruiting

  • Klinik Floridsdorf

    Wien,
    Austria

    Active - Recruiting

  • AZ Delta

    Roeselare,
    Belgium

    Active - Recruiting

  • AZ Nikolaas

    Sint-Niklaas,
    Belgium

    Active - Recruiting

  • CHU UCL Namur asbl - Site Godinne

    Yvoir,
    Belgium

    Site Not Available

  • Ottawa Hospital

    Ottawa,
    Canada

    Site Not Available

  • Ottawa Hospital General Campus

    Ottawa,
    Canada

    Active - Recruiting

  • OCREB

    Toronto,
    Canada

    Site Not Available

  • Princess Margaret Cancer Centre

    Toronto,
    Canada

    Active - Recruiting

  • FN Olomouc

    Olomouc,
    Czechia

    Active - Recruiting

  • University Hospital Na Bulovce

    Praha 8,
    Czechia

    Active - Recruiting

  • University Hospital of Tampere

    Tampere,
    Finland

    Site Not Available

  • Turun Yliopistollinen Keskussairaala

    Turku,
    Finland

    Site Not Available

  • Centre Hospitalier de Cholet

    Cholet,
    France

    Active - Recruiting

  • CHRU Lille

    Lille,
    France

    Site Not Available

  • CHRU Lille

    Lille cedex,
    France

    Active - Recruiting

  • Hôpital du Scorff

    Lorient,
    France

    Active - Recruiting

  • Centre Leon Berard

    Lyon Cedex 08,
    France

    Active - Recruiting

  • Hospital Tenon & University Paris 6

    Paris,
    France

    Active - Recruiting

  • Institut Curie

    Paris,
    France

    Site Not Available

  • Institut Curie - Centre de Lutte Contre le Cancer (CLCC)

    Paris Cedex 05,
    France

    Active - Recruiting

  • CHU de Toulouse Hopital Larrey

    Toulouse,
    France

    Active - Recruiting

  • Hôpital Larrey

    Toulouse,
    France

    Site Not Available

  • Klinikum Chemnitz GmbH

    Chemnitz,
    Germany

    Active - Recruiting

  • Research Site

    Darmstadt,
    Germany

    Site Not Available

  • KKH Grosshansdorf GmbH

    Grosshansdorf,
    Germany

    Active - Recruiting

  • LungenClinic Grosshansdorf GmbH

    Grosshansdorf,
    Germany

    Site Not Available

  • Thoraxklinik-Heidelberg gGmbH

    Heidelberg,
    Germany

    Active - Recruiting

  • Klinik Löwenstein GmbH

    Löwenstein,
    Germany

    Active - Recruiting

  • Haemek Medical Center

    Afula,
    Israel

    Active - Recruiting

  • Assuta Ashdod Institutional Review Board

    Ashdod,
    Israel

    Site Not Available

  • Assuta Ashdod Medical Center

    Ashdod,
    Israel

    Active - Recruiting

  • Bnai Zion Medical Center

    Haifa,
    Israel

    Site Not Available

  • Bnai Zion Medical Center EC

    Haifa,
    Israel

    Site Not Available

  • Bnei-Zion Medical Center

    Haifa,
    Israel

    Active - Recruiting

  • Carmel Medical Center

    Haifa,
    Israel

    Active - Recruiting

  • Institutional Helsinki Committee, The Lady Davis Carmel Medical Center

    Haifa,
    Israel

    Site Not Available

  • Rambam Medical Center - PPDS

    Haifa,
    Israel

    Active - Recruiting

  • Rambam Medical Center EC

    Haifa,
    Israel

    Site Not Available

  • Shaare Zedek Medical Center

    Jerusalem,
    Israel

    Active - Recruiting

  • Shaare Zedek Medical Center EC

    Jerusalem,
    Israel

    Site Not Available

  • Rabin Medical Center Oncology Beilinson Campus

    Petach Tikva,
    Israel

    Active - Recruiting

  • Chaim Sheba Medical Center

    Ramat Gan,
    Israel

    Active - Recruiting

  • Sheba Medical Center - PPDS

    Ramat Gan,
    Israel

    Site Not Available

  • The Chaim Sheba Medical Center EC

    Ramat Gan,
    Israel

    Site Not Available

  • Tel Aviv Sourasky EC

    Tel Aviv,
    Israel

    Site Not Available

  • Tel Aviv Sourasky Medical Center

    Tel Aviv,
    Israel

    Active - Recruiting

  • Tel Aviv Sourasky Medical Center PPDS

    Tel Aviv-Yafo,
    Israel

    Site Not Available

  • Istituto Europeo Di Oncologia

    Milano,
    Italy

    Site Not Available

  • Istituto Europeo di Oncologia

    Milano,
    Italy

    Active - Recruiting

  • Istituto Nazionale Dei Tumori

    Milano,
    Italy

    Active - Recruiting

  • AOU dell'Università degli Studi della Campania Luigi Vanvitelli

    Napoli,
    Italy

    Active - Recruiting

  • Azienda Sanitaria Ospedaliera S Luigi Gonzaga

    Orbassano,
    Italy

    Site Not Available

  • Azienda Sanitaria Ospedaliera S Luigi Gonzaga

    Orbassano (TO),
    Italy

    Site Not Available

  • Istituto Nazionale Tumori Regina Elena

    Roma,
    Italy

    Site Not Available

  • I.F.O. Istituto Nazionale Tumori Regina Elena IRCCS

    Rome,
    Italy

    Active - Recruiting

  • Azienda Sanitaria Ospedaliera S Luigi Gonzaga

    Torino,
    Italy

    Active - Recruiting

  • Ospedale di Circolo

    Varese,
    Italy

    Active - Recruiting

  • VU Medisch Centrum

    Amsterdam,
    Netherlands

    Active - Recruiting

  • Universitair Medisch Centrum Groningen

    Groningen,
    Netherlands

    Site Not Available

  • Universitair Medisch Centrum Groningen - Department of Medical Oncology

    Groningen,
    Netherlands

    Active - Recruiting

  • Leiden University Medical Center

    Leiden,
    Netherlands

    Active - Recruiting

  • Centro Hospitalar de Lisboa Norte, EPE - Hospital de Santa Maria

    Lisboa,
    Portugal

    Active - Recruiting

  • Instituto Português de Oncologia de Lisboa Francisco Gentil, E.P.E.

    Lisboa,
    Portugal

    Site Not Available

  • Centro Hospitalar do Porto

    Porto,
    Portugal

    Site Not Available

  • Centro Hospitalar do Porto E.P.E. Hospital de Santo António

    Porto,
    Portugal

    Active - Recruiting

  • Instituto Portugues de Oncologia Do Porto Francisco Gentil Epe - PPDS

    Porto Covo,
    Portugal

    Active - Recruiting

  • Clinica Tres Torres

    Barcelona,
    Spain

    Active - Recruiting

  • Institut Universitari Dexeus-Quiron - Servei d oncologia medica - Institut Oncologic Dr. Rosell

    Barcelona,
    Spain

    Active - Recruiting

  • Centro Integral Oncologico Clara Campa

    Madrid,
    Spain

    Active - Recruiting

  • Centro Oncologico MD Anderson

    Madrid,
    Spain

    Active - Recruiting

  • Hospital Regional Universitario de Malaga - Hospital General

    Malaga,
    Spain

    Active - Recruiting

  • Hospidal Universitario Ntra. Sra. De Valme

    Sevilla,
    Spain

    Active - Recruiting

  • Hospital Universitario Virgen Macarena

    Sevilla,
    Spain

    Active - Recruiting

  • Hospital Universitari i Politecnic La Fe de Valencia

    Valencia,
    Spain

    Active - Recruiting

  • Complejo Hospitalario Universitario Insular-Materno Infantil

    las Palmas de Gran Canaria,
    Spain

    Active - Recruiting

  • Universitetssjukhuset i Linköping

    Linköping,
    Sweden

    Active - Recruiting

  • Bedford General Hospital

    Bedford,
    United Kingdom

    Active - Recruiting

  • Birmingham Heartlands Hospital

    Birmingham,
    United Kingdom

    Active - Recruiting

  • Queen Elizabeth Hospital Birmingham

    Birmingham,
    United Kingdom

    Site Not Available

  • Royal Bournemouth Hospital

    Bournemouth,
    United Kingdom

    Active - Recruiting

  • The Royal Marsden Hospital

    Chelsea,
    United Kingdom

    Active - Recruiting

  • Royal Surrey County Hospital

    Guildford,
    United Kingdom

    Active - Recruiting

  • Northwick Park Hospital

    Harrow,
    United Kingdom

    Active - Recruiting

  • Clatterbridge Cancer Centre - Liverpool

    Liverpool,
    United Kingdom

    Active - Recruiting

  • Charing Cross Hospital

    London,
    United Kingdom

    Active - Recruiting

  • Preston Hospital

    Preston,
    United Kingdom

    Active - Recruiting

  • Good Hope Hospital

    Sutton Coldfield,
    United Kingdom

    Site Not Available

  • Holy Cross Health

    Fort Lauderdale, Florida 33308-4603
    United States

    Active - Recruiting

  • Research Site

    Rockland, Massachusetts 02370
    United States

    Site Not Available

  • The Ohio State University Wexner Medical Center

    Columbus, Ohio 43221
    United States

    Active - Recruiting

  • Vanderbilt University Medical Center

    Nashville, Tennessee 37212
    United States

    Active - Recruiting

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