Potassium Citrate and Crystal Light Lemonade

Last updated: July 30, 2024
Sponsor: Northwestern University
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

Potassium citrate + crystal light

Crystal light

Potassium citrate

Clinical Study ID

NCT05389995
STU00216084
  • Ages 18-80
  • All Genders

Study Summary

To define the effect of crystal light, potassium citrate, or both on urinary stone risk factors in patients with a history of stone and hypocitraturia/low pH

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Men and women between age 18-80 years

  2. Willing to follow experimental protocol

  3. Willing to complete 24-hour urine collections (three total)

  4. Willing to sign the informed consent form

  5. Completed Litholink Collection with blood work with results a. hypocitraturia OR aciduria i. Hypocitraturics must meet definition of < 450mg/day for men < 550 mg/day for women. b. Low urine pH must be less than 5.6 c. potassium, BUN, creatinine, eGFR andhemoglobin A1c within normal limits

Exclusion

Exclusion Criteria:

  1. Patients with severe hypocitraturia < 200 mg/day (men or women)

  2. Patients with hyperkalemia, uncontrolled diabetes, chronic kidney disease, adrenalinsufficiency, delayed gastric emptying (or drug induced delayed gastric emptying),peptic ulcer disease, or active UTI

  3. Patients with distal renal tubular acidosis or medication induced RTA (e.g. carbonicanhydrase inhibitor, topiramate)

  4. Members of vulnerable patient populations

  5. Allergies to ingredients in crystal light

  6. Patients lacking decisional capacity

Study Design

Total Participants: 10
Treatment Group(s): 3
Primary Treatment: Potassium citrate + crystal light
Phase:
Study Start date:
August 01, 2022
Estimated Completion Date:
March 31, 2025

Connect with a study center

  • Northwestern University

    Chicago, Illinois 60611
    United States

    Active - Recruiting

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