Austrian Registry for Evaluation of Treatment Patterns and Outcome in Patients With Advanced Pancreatic Ductal Adenocarcinoma (PDAC)

Last updated: November 18, 2025
Sponsor: Medical University of Graz
Overall Status: Active - Recruiting

Phase

N/A

Condition

Adenocarcinoma

Pancreatic Cancer

Digestive System Neoplasms

Treatment

all approved chemotherapeutic agents from second line

Clinical Study ID

NCT05526443
ADPACA
  • Ages > 18
  • All Genders

Study Summary

To systematically collect and analyse real-world data on treatment patterns, clinical outcomes and toxicities among patients with advanced pancreatic ductal adenocarcinoma (PDAC) undergoing systematic treatment in Austria

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • 18 years, female and male

  • ECOG (Eastern Cooperative Oncology Group) Scale 0-2

  • Diagnosis of histologically confirmed locally advanced inoperable and/or metastaticPDAC

  • Patients undergoing palliative 1st line therapy with a platinum- or gemcitabine-based chemotherapy in case of previous (neo)adjuvant therapy also patients whoreceive nal-Irinotecan/5-FU/Leukovorin as palliative first line are eglible

  • Signed informed consent for prospective patients, for retrospective cases noinformed consent is required

Exclusion

Exclusion Criteria:

  • Patients with locally advanced operable PDAC who do not receive palliativechemotherapy

  • Patients with locally advanced borderline resectable PDAC who do not receivepalliative chemotherapy

Study Design

Total Participants: 1500
Treatment Group(s): 1
Primary Treatment: all approved chemotherapeutic agents from second line
Phase:
Study Start date:
January 13, 2023
Estimated Completion Date:
September 30, 2027

Study Description

1500 adult patients with locally advanced inoperable and/or metastasized PDAC undergoing first line chemotherapy

Connect with a study center

  • Medical University Graz Department of Oncology

    Graz, Styria 8036
    Austria

    Active - Recruiting

  • Medical University Graz Department of Oncology

    Graz 2778067, Styria 2764581 8036
    Austria

    Active - Recruiting

  • Ordensklinikum Linz

    Linz, Upper Austria 4010
    Austria

    Site Not Available

  • Ordensklinikum Linz

    Linz 2772400, Upper Austria 2769848 4010
    Austria

    Active - Recruiting

  • Landesklinikum Amstetten

    Amstetten 2782555, 3300
    Austria

    Active - Recruiting

  • Landesklinikum Feldkirch

    Feldkirch 2779674, 6800
    Austria

    Active - Recruiting

  • Krankenhaus der Barmherzigen Brüder

    Graz, 8020
    Austria

    Site Not Available

  • Krankenhaus der Barmherzigen Brüder

    Graz 2778067, 8020
    Austria

    Active - Recruiting

  • Universitätsklinikum Innsbruck,

    Innsbruck, 6020
    Austria

    Site Not Available

  • Universitätsklinikum Innsbruck,

    Innsbruck 2775220, 6020
    Austria

    Active - Recruiting

  • Landesklinikum Klagenfurt

    Klagenfurt, 9020
    Austria

    Site Not Available

  • Landesklinikum Klagenfurt

    Klagenfurt 2774326, 9020
    Austria

    Active - Recruiting

  • Universitätsklinikum St. Pölten

    Sankt Pölten 2766429, 3100
    Austria

    Active - Recruiting

  • Universitätsklinikum St. Pölten

    St. Pölten, 3100
    Austria

    Site Not Available

  • Barmherzige Schwestern Krankenhaus Wien

    Vienna 2761369, 1060
    Austria

    Active - Recruiting

  • Pancreatic Cancer Unit des Comprehensive Cancer Center (CCC-PCU)

    Vienna 2761369, 1090
    Austria

    Active - Recruiting

  • St. Josef Krankenhaus Wien

    Vienna 2761369, 1130
    Austria

    Active - Recruiting

  • Pancreatic Cancer Unit des Comprehensive Cancer Center (CCC-PCU)

    Wien, 1090
    Austria

    Site Not Available

  • Krankenhaus St. Vinzenz Zams

    Zams 2760749, 6511
    Austria

    Active - Recruiting

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