The MIRIA Acne Scar Study

Inclusion Criteria:

• Subjects 18-65 years of age

• Acne scars on the face

• Able and willing to comply with all study procedures and at home care; and,

• Able and willing to give informed consent.

Exclusion Criteria:

• Hypersensitive to light in the near infrared wavelength region

• On medication known to increase sensitivity to sunlight

• Seizure disorder triggered by light

• Takes or has taken oral isotretinoin, such as Accutane®, within the last six months

• Use of topical over the counter or prescription retinoids such as Retinol creams,gels, Tazarotene, Tretinoin, Adapalene, within the last 30 days

• Active acne or rosacea

• Active localized or systemic infection, or an open wound or abscess in area beingtreated

• Significant systemic inflammatory disease or illness, such as lupus, or an illnesslocalized in area being treated

• Common acquired nevi that are predisposed to the development of malignant melanoma

• Current or prior herpes simplex in the target treatment area

• Is receiving or has received gold therapy

• Currently enrolled in an investigational drug or device trial, or has received aninvestigational drug or was treated with an investigational device within in thearea to be treated 6 months prior to study entry

• Facial cosmetic procedures in the target areas within previous 6 months (e.g., laseror other energy-based device treatment, microdermabrasion, injection of dermalfiller)

• Micro-needling and/or chemical peel on the target treatment area in the past 3months

• Injection of cosmetic neurotoxins such as botulinum toxin in the treatment areaswithin the previous 3 months of standard duration toxins, and 6 months for longlasting neurotoxin therapy

• Significant uncontrolled concurrent illness, such as diabetes mellitus,hypertension, or cardiovascular disease

• History of immunosuppression/immune deficiency disorder or currently usingimmunosuppressive medications

• Planned weight loss of greater than five pounds

• Facial hair in the treatment areas which would prevent evaluation of the outcomemeasures. For men, must be clean shaven in the area of treatment

• Any condition or situation which, in the investigators opinion, may put the subjectat significant risk, may confound study results or may interfere significantly withthe subject's participation

• Is pregnant or of childbearing potential and not using medically effective birthcontrol, or has been pregnant in the last 3 months, is currently breast feeding orplanning a pregnancy during the study.

• Has had unprotected sun exposure within four weeks of treatment, including the useof tanning beds or plans for unprotected sun exposure during the course of thestudy,

• Has used tanning products, such as creams, lotions and sprays within four weeksprior to treatment.

• Coagulation disorder or currently using anti-platelet/anticoagulation medication,including use of aspirin, or fish oil supplements

• Taking medications that alter the wound-healing response or evidence of compromisedwound healing

• Known history of keloid formation

• Known history of medical diseases that may cause koebnerization (the appearance ofdisease in another location), such as vitiligo, psoriasis or lichen planus

• History of skin cancer or suspicious lesions in treatment area

• Subject is relocating out of the zone of the study site (ie. Moving out of state orabout 50+ miles away from study area)

• Subject has history or active melasma or other pigmentary disorders such asvitiligo.