0.01% Hypochlorous Acid in the Treatment of Blepharitis

Last updated: November 4, 2022
Sponsor: Eye & ENT Hospital of Fudan University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Blepharitis

Treatment

N/A

Clinical Study ID

NCT05608980
0.01% Hypochlorous Acid
  • Ages > 18
  • All Genders

Study Summary

This is a multi-center, multidisciplinary, open-label, randomized controlled prospective clinical study.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Age 18 or older.
  2. Anterior or mixed (anterior + posterior) blepharitis.
  3. Similar clinical condition of both eyes.
  4. A negative urine pregnancy test result for women of childbearing potential
  5. Normal lid position and closure
  6. Ability to understand and provide informed consent to participate in this study
  7. Willingness to follow study instructions and likely to complete all required visits.

Exclusion

Exclusion Criteria:

  1. Any ocular surface disease other than blepharitis.
  2. Known allergy to hypochlorous acid or boric acid.
  3. Eye surgery in the last 6 months.
  4. History of Stevens-Johnson syndrome or ocular pemphigoid
  5. Ocular trauma in the last 6 months.
  6. Use of contact lenses in the last 6 months.
  7. Pregnancy or lactation.
  8. Daily use of makeup on lashes.
  9. Any ocular or systemic medication that might affect the ocular microbiota (antibiotics, immunosuppressants, steroids).
  10. Pregnant or lactating women
  11. Signs of current infection, including fever and current treatment with antibiotics
  12. Liver, renal, or hematologic disease
  13. The use of any other investigational drug

Study Design

Total Participants: 100
Study Start date:
July 01, 2022
Estimated Completion Date:
May 01, 2023

Connect with a study center

  • Eye & ENT Hospital of Fudan University

    Shanghai, Shanghai
    China

    Active - Recruiting

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