Phase 3 Study of KP-100LI in Subjects With Vocal Fold Scar

Inclusion Criteria:

1. 18 years to 75 years

2. Presence of bilateral vocal fold scar or sulcus diagnosed

3. No other vocal lesion or vocal movement disorder

4. Voice Handicap Index-10 (VHI-10) score of 11 or higher

5. No laryngoplasty, collagen or lipid infusion to vocal cord, removal scar, fascialgraft, or administration of steroid or hyaluronic acid to vocal cord

Exclusion Criteria:

1. No movement disorders of the vocal fold including paralysis

2. Airway disease caused by burn

3. History of malignant tumor

4. History of allergy to local anesthesia agent

5. With impaired coagulation-fibrinolysis, or taking anticoagulant or antiplateletdrugs

6. Serious concomitant disease

7. Pregnant (including suspected), nursing, wishing to become pregnant, or unable toprevent conception during the trial period using contraceptive methods