Melatonin vs Gabapentin for Post Trauma Surgery

Last updated: January 24, 2023
Sponsor: All India Institute of Medical Sciences, New Delhi
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

N/A

Clinical Study ID

NCT05699876
AIIMS Delhi
  • Ages 18-65
  • All Genders

Study Summary

This project aims to compare the effect of preoperative administration of melatonin and gabapentin in reducing preoperative anxiety, stress markers and postoperative pain levels in trauma patients undergoing surgery. Gabapentin has analgesic as well as sedative properties. Melatonin, a hormone has been extensively used in intensive care units and has found to improve the sleep cycle and reduce pain. It is now being explored as a preoperative medication.

Eligibility Criteria

Inclusion

Inclusion criteria: Patients will be recruited if they satisfy the following inclusioncriteria:

  • Age 18-65 years,
  • ASA score I-II,
  • Scheduled either for non-emergency surgery after trauma and
  • Presumptive duration of operation not exceeding 3 hours.

Exclusion

Exclusion criteria: The following patients will be excluded from the study:

  • Patients for emergency surgeries
  • Surgeries taking place after 1pm (to account for diurnal variation in cortisol levels)
  • Patients having altered mental state, history of psychiatric disorder, history of drugabuse or those on chronic pain medication
  • Patients who have come for a repeat surgery and have already been included once in thestudy

Study Design

Total Participants: 70
Study Start date:
January 15, 2023
Estimated Completion Date:
November 30, 2023

Connect with a study center

  • Aiims

    New Delhi, Delhi 110029
    India

    Active - Recruiting

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