A Study to Evaluate Intravitreal JNJ-81201887 (AAVCAGsCD59) Compared to Sham Procedure for the Treatment of Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

Inclusion Criteria:

• Have non-subfoveal (defined as not involving the center point of the fovea)geographic atrophy (GA) secondary to age-related macular degeneration (AMD) with anarea that can be measured and measures 2.5 millimeter square (mm^2) to 17.5 mm^2 (1-and 7- disc areas respectively), determined by the central reading center (CRC) fromscreening images of fundus autofluorescence (FAF) and spectral domain opticalcoherence tomography (SD-OCT)

• If GA is multifocal, at least one focal lesion must be greater than or equal to (>=) 1.25 mm^2 (0.5- disc area), as assessed by the CRC

• GA can be photographed in its entirety by FAF, using a 30- degree image centered onthe fovea, as assessed by the CRC

• Fellow eye must be present with a best corrected distance visual acuity (BCVA) ofcounting fingers or better

• Man or woman (according to their reproductive organs and functions assigned bychromosomal complement)

Exclusion Criteria:

• History of transpupillary thermotherapy, photodynamic therapy or external-beamradiation therapy in the region of study eye

• Any prior thermal laser in the macular region, regardless of indication

• History of retinal detachment (with or without repair)

• Active, infectious conjunctivitis, keratitis, scleritis, or endophthalmitis

• Any sign of diabetic retinopathy or central serous chorioretinopathy