Phase
Condition
Diabetes And Hypertension
Diabetes Mellitus, Type 2
Diabetes Prevention
Treatment
Semaglutide
Insulin Icodec
Clinical Study ID
Ages > 18 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
- Diagnosed with type 2 diabetes (T2D) greater than or equal to (>=) 180 days prior tothe day of screening
- HbA1c from 7.5%-10.5% (58-91 millimoles per mole [mmol/mol]) (both inclusive)
- Treated with once daily or twice daily basal insulin (minimum of 0.25 internationalunits per kilograms per day (IU/kg/day) or 20 IU/day) without concomitantglucagon-like peptide-1 receptor agonists (GLP-1 RA) >= 90 days prior to the day ofscreening with or without any of the following antidiabetic drugs/regimens with stabledoses >= 90 days prior to screening: metformin, sulfonylureas, meglitinides (glinides), dipeptidyl peptidase-4 (DPP-4) inhibitors, Sodium-glucose Cotransporter-2 (SGLT2) inhibitors, thiazolidinediones, alpha-glucosidase inhibitors. Oral combinationproducts (for the allowed individual oral anti-diabetic drugs)
Exclusion
Exclusion Criteria:
- Presence or history of pancreatitis (acute or chronic) within 180 days beforescreening
- Myocardial infarction, stroke, hospitalisation for unstable angina pectoris ortransient ischaemic attack within 180 days prior to the day of screening and betweenscreening and initiation
- Chronic heart failure classified as being in New York Heart Association (NYHA) ClassIV at screening
- Planned coronary, carotid or peripheral artery revascularization
- Uncontrolled and potentially unstable diabetic retinopathy or maculopathy. Verified bya fundus examination performed within the past 90 days prior to screening or in theperiod between screening and initiation. Pharmacological pupil-dilation is arequirement unless using a digital fundus photography camera specified for non-dilatedexamination
Study Design
Connect with a study center
Edumed Broumov
Broumov, 550 01
CzechiaSite Not Available
Novo Nordisk Investigational Site
Broumov, 550 01
CzechiaSite Not Available
Diabetologické centrum s.r.o.
Olomouc, 779 00
CzechiaSite Not Available
Novo Nordisk Investigational Site
Olomouc, 779 00
CzechiaSite Not Available
Novo Nordisk Investigational Site
Plzeň, 301 00
CzechiaSite Not Available
DIALINE s.r.o.
Plzeň 3, 301 00
CzechiaSite Not Available
Novo Nordisk Investigational Site
Plzeň 3, 301 00
CzechiaSite Not Available
Diabetologická a endokrinologická ambulance Praha
Praha, 140 21
CzechiaSite Not Available
Novo Nordisk Investigational Site
Praha, 140 21
CzechiaSite Not Available
Diabet2 s.r.o.
Praha 1, 110 00
CzechiaActive - Recruiting
Novo Nordisk Investigational Site
Praha 1, 110 00
CzechiaSite Not Available
Medicon a.s.
Praha 4, 140 00
CzechiaSite Not Available
Novo Nordisk Investigational Site
Praha 4, 140 00
CzechiaSite Not Available
Comfort Care Praha s.r.o.
Praha 4 - Chodov, 148 00
CzechiaSite Not Available
Novo Nordisk Investigational Site
Praha 4 - Chodov, 148 00
CzechiaSite Not Available
EUC Klinika Praha a.s.
Praha 5, 150 00
CzechiaSite Not Available
Novo Nordisk Investigational Site
Praha 5, 150 00
CzechiaSite Not Available
Hospital Universiti Kebangsaan Malaysia
Cheras, Kuala Lumpur 56000
MalaysiaSite Not Available
Novo Nordisk Investigational Site
Cheras, Kuala Lumpur 56000
MalaysiaActive - Recruiting
Hospital Miri
Sarawak, Miri 98000
MalaysiaSite Not Available
Novo Nordisk Investigational Site
Sarawak, Miri 98000
MalaysiaActive - Recruiting
Novo Nordisk Investigational Site
Sungai Buloh, Selangor 47000
MalaysiaSite Not Available
Universiti Teknologi MARA, Sungai Buloh Campus
Sungai Buloh, Selangor 47000
MalaysiaSite Not Available
Hospital Putrajaya
Putrajaya, Wilayah Persekutuan Putrajaya 62250
MalaysiaSite Not Available
Novo Nordisk Investigational Site
Putrajaya, Wilayah Persekutuan Putrajaya 62250
MalaysiaActive - Recruiting
Specjalistyczny Gabinet Diabetologiczny Radoslaw Rumianowski
Gorzow Wielkopolski, Lubuskie 66-400
PolandSite Not Available
Med. Cent. Diabet. Endo. Metabol. DIAB-ENDO-MET
Krakow, Malopolskie 31-261
PolandSite Not Available
Novo Nordisk Investigational Site
Krakow, Malopolskie 31-261
PolandSite Not Available
Novo Nordisk Investigational Site
Tarnow, Malopolskie 33-100
PolandSite Not Available
Osrodek Badan Klinicznych "METABOLICA" lek. Robert Witek
Tarnow, Malopolskie 33-100
PolandSite Not Available
NBR Polska
Warszawa, Mazowieckie 00-710
PolandSite Not Available
Novo Nordisk Investigational Site
Warszawa, Mazowieckie 00-710
PolandSite Not Available
Novo Nordisk Investigational Site
Bialystok, 15-351
PolandSite Not Available
Osteo-Medic s.c. A. Racewicz, J. Supronik
Bialystok, 15-351
PolandSite Not Available
Centrum Badan Klinicznych PI-House
Gdansk, 80-546
PolandSite Not Available
NZOZ Gdanska Poradnia Cukrzycowa
Gdansk, 80-858
PolandSite Not Available
NZOZ Gdanska Poradnia Cukrzycowa Sp.z o.o.
Gdansk, 80-858
PolandSite Not Available
Novo Nordisk Investigational Site
Gdansk, 80-858
PolandSite Not Available
Novo Nordisk Investigational Site
Gorzow Wielkopolski, 66-400
PolandSite Not Available
Centrum Medyczne Pratia Katowice
Katowice, 40-081
PolandSite Not Available
Novo Nordisk Investigational Site
Katowice, 40-081
PolandSite Not Available
Novo Nordisk Investigational Site
Lodz, 90-302
PolandSite Not Available
Santa Sp. z o.o, Santa Familia Centrum Badan, Profilaktyki i Leczenia
Lodz, 90-302
PolandActive - Recruiting
NBR Polska Tomasz Klodawski
Warszawa, 00-710
PolandSite Not Available
Novo Nordisk Investigational Site
Wierzchoslawice, 33-122
PolandSite Not Available
Poradnia Chorob Metabolicznych w Wierzchoslawicach
Wierzchoslawice, 33-122
PolandSite Not Available
Clin. Centre Vojvodina, Clin. endocr., diab. and met. dis.
Novi Sad, Vojvodina 21000
SerbiaActive - Recruiting
Novo Nordisk Investigational Site
Novi Sad, Vojvodina 21000
SerbiaActive - Recruiting
CHC Zvezdara, Clinical department for endocrinology
Belgrade, 11000
SerbiaSite Not Available
Clinical Hospital Centre Zemun
Belgrade, 11080
SerbiaActive - Recruiting
Novo Nordisk Investigational Site
Belgrade, 11000
SerbiaActive - Recruiting
Clinical Centre Kragujevac, Internal Diseases Clinic, Endocr
Kragujevac, 34000
SerbiaActive - Recruiting
Clinical Centre Kragujevac, Internal Diseases Clinic, Endocrinology department
Kragujevac, 34000
SerbiaSite Not Available
Novo Nordisk Investigational Site
Kragujevac, 34000
SerbiaActive - Recruiting
King Chulalongkorn Memorial Hospital
Bangkok, 10330
ThailandSite Not Available
Novo Nordisk Investigational Site
Bangkok, 10330
ThailandSite Not Available
Rajavithi Hospital
Bangkok, 10400
ThailandSite Not Available
Ramathibodi Hospital - Ped-Endo and Metabolism
Bangkok, 10400
ThailandSite Not Available
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