Prevention of Cardiovascular Disease and Mortality in Patients With Psoriasis or Psoriatic Arthritis

Last updated: October 9, 2025
Sponsor: University of Pennsylvania
Overall Status: Active - Recruiting

Phase

N/A

Condition

Rosacea

Psoriatic Arthritis

Skin Wounds

Treatment

Care Coordinator Model

Clinical Study ID

NCT05908240
853218
  • Ages 40-75
  • All Genders

Study Summary

The goal of this research is to test a novel centralized care coordinator program to assist patients with psoriatic disease in lowering their risk of cardiovascular disease through the application of standard of care approaches to improving modifiable cardiovascular risk factors.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Willing and able to provide informed consent

  2. Male or female aged 40-75

  3. Being seen by a dermatology provider in routine care for the primary encounterdiagnosis of psoriasis

Exclusion

Exclusion Criteria:

  1. Currently taking a prescription lipid lowering medication

  2. Pregnant or planning pregnancy in the next 6 months

  3. Has a known history of cardiovascular disease (MI, Stroke, coronary artery,cerebrovascular, or peripheral vascular disease)

Study Design

Total Participants: 520
Treatment Group(s): 1
Primary Treatment: Care Coordinator Model
Phase:
Study Start date:
June 15, 2023
Estimated Completion Date:
July 31, 2026

Study Description

Psoriasis patients have an increased risk of cardiovascular disease and mortality but are less likely to have traditional cardiovascular risk factors identified or adequately managed. Care coordinators have previously been demonstrated to improve outcomes in patients with chronic diseases (such as comorbid diabetes and depression) and are now routinely embedded in primary care practices in integrated health systems. The goal of this research is to test a novel centralized care coordinator program to assist patients with psoriatic disease in lowering their risk of cardiovascular disease through the application of standard of care approaches to improving modifiable cardiovascular risk factors.

Connect with a study center

  • Johnson Dermatology

    Fort Smith, Arkansas 72916
    United States

    Site Not Available

  • Johnson Dermatology

    Fort Smith 4111410, Arkansas 4099753 72916
    United States

    Active - Recruiting

  • Dawes Fretzin Clinical Research

    Columbus, Indiana 47201
    United States

    Site Not Available

  • Dawes Fretzin Clinical Research

    Indianapolis, Indiana 46250
    United States

    Site Not Available

  • Dawes Fretzin Clinical Research

    Columbus 4256038, Indiana 4921868 47201
    United States

    Active - Recruiting

  • Dawes Fretzin Clinical Research

    Indianapolis 4259418, Indiana 4921868 46250
    United States

    Active - Recruiting

  • MiSkinCenter

    Northville, Michigan 48167
    United States

    Site Not Available

  • MiSkinCenter

    Northville 5003956, Michigan 5001836 48167
    United States

    Active - Recruiting

  • SUNY Downstate

    Brooklyn, New York 11203
    United States

    Site Not Available

  • SUNY Downstate

    Brooklyn 5110302, New York 5128638 11203
    United States

    Active - Recruiting

  • City Dermatology

    Bensalem, Pennsylvania 19020
    United States

    Site Not Available

  • University of Pennsylvania

    Philadelphia, Pennsylvania 19104
    United States

    Site Not Available

  • City Dermatology

    Bensalem 5179995, Pennsylvania 6254927 19020
    United States

    Active - Recruiting

  • University of Pennsylvania

    Philadelphia 4560349, Pennsylvania 6254927 19104
    United States

    Active - Recruiting

  • University of Utah

    Salt Lake City, Utah 84112
    United States

    Site Not Available

  • University of Utah

    Salt Lake City 5780993, Utah 5549030 84112
    United States

    Active - Recruiting

  • University of Virginia

    Charlottesville, Virginia 22903
    United States

    Site Not Available

  • University of Virginia

    Charlottesville 4752031, Virginia 6254928 22903
    United States

    Active - Recruiting

  • Bellevue Dermatology Clinic

    Bellevue, Washington 98004
    United States

    Site Not Available

  • Bellevue Dermatology Clinic

    Bellevue 5786882, Washington 5815135 98004
    United States

    Active - Recruiting

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