Effect of Maolactin on Gastrointestinal Tract (GIT) Health

Inclusion Criteria:

• Adults 18 years and over

• Generally healthy

• BMI <35kg/m2

• Able to provide informed consent

• Agree to not participate in another clinical trial while enrolled in this trial

• Females using a prescribed form of birth control (e.g. oral contraceptive)

• Experiencing moderate GI disturbances of the upper GI tract - 1 or multiple symptoms (reflux, heartburn, regurgitation, nausea, bloating, abdominal pain) at least once aweek for at least 3 months.

• Normal dietary habits (no FODMAP diet, elimination diet, vegan diet, etc) with aminimum 2-month period of self-reported dietary stability.

• Agree to not change current diet and/or exercise frequency or intensity duringentire study period

• Agree to not use any dietary supplements for gut health or digestive enzymes duringthe study period

Exclusion Criteria:

• Unstable(1) or serious illness (e.g. serious mood disorders such as depression orbipolar disorder, neurological disorders such as MS, kidney disease, liver disease,heart conditions, diabetes, thyroid gland dysfunction)

• People with a past or current history of GIT conditions e.g. inflammatory boweldisease, celiac disease or cystic fibrosis as well as gastrointestinal tract surgery

• Current malignancy (excluding BCC) or chemotherapy or radiotherapy treatment formalignancy within the previous 2 years

• Currently taking any proton pump inhibitors [e.g., pantoprazole (Somac), rabeprazole (Pariet), omeprazole (Losec) or any anticoagulation or antiplatelet medications [e.g. Coumadin (Warfarin), Heparin, Dalteparin, Enoxaparin, dabigatran (Pradaxa),rivaroxaban (Xarelto), apixaban (Eliquis), edoxaban (Savaysa), betrixaban (Bevyxxa),clopidogrel (Plavix), prasugrel (Effient), ticagrelor (Brilinta), cilostazol (Pletal) and dipyridamole (Attia, Ofcram, Persantin, Persantin Retard, Trolactin)]including low dose aspirin (acetylsalicylic acid)

• Active smokers, nicotine use or drug (prescription or illegal substances) abuse

• Allergic to any of the ingredients in active or placebo formula

• Pregnant or lactating woman or women trying to conceive

• Any condition which in the opinion of the investigator makes the participantunsuitable for inclusion (including hypercholesterolemia)

• Currently participating in any other clinical trial

Footnote

(1)An unstable illness is any illness that is currently not being treated with a stable dose of medication or is fluctuating in severity. A serious illness is a condition that carries a risk of mortality, negatively impacts quality of life and daily function and/or is burdensome in symptoms and/or treatments.