Blood Flow Restriction Training in Multiple Sclerosis

Last updated: November 16, 2023
Sponsor: Cairo University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Multiple Sclerosis

Memory Loss

Neurologic Disorders

Treatment

strengthening ex

strengthening ex with BFR training

Clinical Study ID

NCT06143930
BFR in MS
  • Ages 18-45
  • All Genders

Study Summary

Traditional physical therapy resisted training for people with MS have been shown to be beneficial; however, their usefulness has been limited by fatigue. The effect of blood flow restriction on strength and other measures of physical function was demonstrated in healthy populations and those with chronic disease. This study may add missing information to the existing literature and suggests directions for research on the effectiveness of BFR training on individuals with relapsing and remitting MS.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Patients were diagnosed with MS by a neurologist according to McDonald's criteria 2010
  2. Expanded Disability Status Scale (EDSS) scores ranging from 2.5 to 5.5 .
  3. Patient able to walk 100 meters or more.
  4. No change within MS specific medication three months from the study.
  5. Last Ms Attack from more than two months.

Exclusion

Exclusion Criteria: 1. Multiple sclerosis patients with other neurological or orthopedic problems. 2. Multiple sclerosis patients with systemic problems (cardiovascular or pulmonarydiseases…). 3. Patients with cognitive impairment. 4. Pregnant female patients. 5. Patients in acute relapse stage.

Study Design

Total Participants: 48
Treatment Group(s): 2
Primary Treatment: strengthening ex
Phase:
Study Start date:
July 01, 2023
Estimated Completion Date:
July 31, 2024

Study Description

Multiple sclerosis patients are characterized by impaired functional capacity which is related to reduce muscle strength affecting predominantly the lower extremity.

Resistance training (RT) has proven to be one of the interventions in MS patients showing a consistent and positive effect on muscle strength and on parameters directly related to lower extremity physical function (eg, walking performance and stair negotiation).

Training with blood flow restriction (BFR), is an increasingly common clinical intervention among physical therapists over the past decade and consistent with the evidence. It has been investigated in people with neurological disorders including stroke and incomplete Spinal Cord Injuries. Research is limited on the use of BFR for individuals with MS.

Connect with a study center

  • Faculty of physical therapy

    Giza, +20
    Egypt

    Active - Recruiting

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