Comparative PK Study Of THC/CBD Formulations

Inclusion Criteria:

1. Subjects must be 21-65 years old.
2. Subjects must have a signed study informed consent before any procedure.
3. Subjects must have a cannabis license as detailed at procedure No. 106 of the IMC-GCO , license will be issued and approved by PI at screening visit after signing oninformed consent.
4. Female subjects must be of non-childbearing potential or, if of childbearingpotential, must have a negative urine pregnancy test at screening, visit 1 and visit

Exclusion Criteria:

1. A history of allergic reactions attributed to compounds of similar chemical orbiologic composition to THC/CBD.
2. Has an underlying medical condition that would preclude study participation.
3. Chronic use of medications for underlying medical conditions.
4. Use of any medications within 24 hours prior to treatment visit.
5. Is currently participating in another study of an investigational agent/medicaldevice.
6. Has known psychiatric or substance abuse disorders that would interfere withparticipating in the study.
7. Patients who previously suffered from dysfunction of the: liver, kidneys, heart, bloodvessels and immune system (such as transplant recipients or patients undergoingchemotherapy).
8. Patients who previously suffered from depression or anxiety.
9. Medical history of high blood pressure, low blood pressure or diabetes.
10. Patients who experience difficulties in performing daily activities.
11. Current cannabis use or positive THC urine test results.
12. Pregnant or lactating female subjects