Caries Detection With Two Different Caries Detecting Devices

Last updated: April 7, 2025
Sponsor: Tufts University
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

LumiCare rinse

QLF Inspektor Pro Imaging

Calcivis Dental Imaging

Clinical Study ID

NCT06152081
STUDY00003913
  • Ages > 21
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

The primary aim of this study will be to compare the effectiveness of the novel LumiCare™ rinse and with QLF in determining caries progression. The secondary aim is to compare the progression of carious lesions between patients who reported use of e-cigarettes/vapes and those who did not.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patients of TUSDM Comprehensive Care Clinic

  • Adult patients over the age of 21

  • Extreme/High Caries Risk classification per TUSDM Caries Management by RiskAssessment (CAMBRA) form

  • Presence of 2 or more initial active primary carious lesions on a free coronalsurface of any tooth by visual assessment, QLF, and LumiCare™

  • Presence of at least 1 cavitated lesion

  • Updated (no more than 6 months old) bite wing radiographs available.

  • Patients who responded either yes/no to use of e-cigarettes/vapes

  • 1 active caries, 1 inactive caries and 1 sound tooth surface.

Exclusion

Exclusion Criteria:

  • Low or moderate caries risk classification per TUSDM CAMBRA form

  • No clinically detectable carious lesions on free coronal surfaces

  • No cavitated caries lesions

  • Carious teeth with caries lesions concomitant with extrinsic stains, fluorosis, ordevelopmental defects.

  • Patients who responded yes to the use of conventional cigarettes or smokelesstobacco

Study Design

Total Participants: 60
Treatment Group(s): 3
Primary Treatment: LumiCare rinse
Phase:
Study Start date:
April 01, 2025
Estimated Completion Date:
October 31, 2027

Connect with a study center

  • Tufts University School of Dental Medicine

    Boston, Massachusetts 02111
    United States

    Active - Recruiting

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