A Study of LY3972406 in Adult Participants With Moderate-to-Severe Plaque Psoriasis

Last updated: March 3, 2025
Sponsor: Eli Lilly and Company
Overall Status: Active - Not Recruiting

Phase

2

Condition

Psoriasis And Psoriatic Disorders

Warts

Rash

Treatment

LY3972406

Placebo

Clinical Study ID

NCT06176768
18692
2023-504485-39-00
J4H-MC-FVAA
  • Ages 18-75
  • All Genders

Study Summary

The main purpose of this study is to determine the efficacy and safety of LY3972406 in adult participants with moderate-to-severe plaque psoriasis.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Have moderate-to-severe chronic plaque psoriasis for at least 6 months prior tobaseline

  • Have venous access sufficient to allow for blood sampling

  • Are able to swallow oral medication

Exclusion

Exclusion Criteria:

  • Have any other skin conditions, excluding plaque psoriasis

  • Have a current or recent acute, active infection

  • Have manifestations of other autoimmune diseases, such as systemic lupuserythematosus.

  • Are lactating or breastfeeding women

Study Design

Total Participants: 75
Treatment Group(s): 2
Primary Treatment: LY3972406
Phase: 2
Study Start date:
December 06, 2023
Estimated Completion Date:
July 31, 2025

Connect with a study center

  • dermMedica Sp. z o.o.

    Wrocław, Dolnośląskie 51-503
    Poland

    Site Not Available

  • DermoDent Centrum Medyczne Aldona Czajkowska Rafał Czajkowski s.c.

    Osielsko, Kujawsko-pomorskie 86-031
    Poland

    Site Not Available

  • Specderm Poznanska

    Bialystok, Podlaskie 15-375
    Poland

    Site Not Available

  • Centrum Badan Klinicznych PI-House sp. z o.o.

    Gdansk, Pomorskie 80-546
    Poland

    Site Not Available

  • DERMED Centrum Medyczne Sp. z o.o.

    Lodz, Łódzkie 90-265
    Poland

    Site Not Available

  • GCM Medical Group, PSC - Hato Rey Site

    San Juan, 917
    Puerto Rico

    Site Not Available

  • Dermatology Research Associates

    Los Angeles, California 90045
    United States

    Site Not Available

  • Clinical Science Institute

    Santa Monica, California 90404
    United States

    Site Not Available

  • Driven Research

    Coral Gables, Florida 33134
    United States

    Site Not Available

  • Conquest Research

    Winter Park, Florida 32789
    United States

    Site Not Available

  • Psoriasis Treatment Center of Central New Jersey

    East Windsor, New Jersey 08520
    United States

    Site Not Available

  • Schweiger Dermatology Group

    Hackensack, New Jersey 07601
    United States

    Site Not Available

  • Metropolitan Dermatology - Clark

    Kenilworth, New Jersey 07033
    United States

    Site Not Available

  • Accellacare - Winston-Salem

    Winston-Salem, North Carolina 27103
    United States

    Site Not Available

  • Remington Davis Clinical Research

    Columbus, Ohio 43215
    United States

    Site Not Available

  • Remington-Davis, Inc

    Columbus, Ohio 43215
    United States

    Site Not Available

  • Oregon Dermatology and Research Center

    Portland, Oregon 97210
    United States

    Site Not Available

  • DermDox Centers for Dermatology

    Camp Hill, Pennsylvania 17011
    United States

    Site Not Available

  • Accellacare, US Inc., d/b/a Accellacare of Knoxville

    Jefferson City, Tennessee 37760
    United States

    Site Not Available

  • Austin Institute for Clinical Research

    Houston, Texas 77056
    United States

    Site Not Available

  • Center for Clinical Studies

    Houston, Texas 77004
    United States

    Site Not Available

  • Virginia Clinical Research, Inc.

    Norfolk, Virginia 23502
    United States

    Site Not Available

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