A Study of TL-925 Ophthalmic Emulsion as a Treatment for Dry Eye Disease

Inclusion Criteria:

• A diagnosis of dry eye disease for at least 6 months

• An unanesthetized Schirmer's test score (STS) of ≤ 10mm and ≥ 1mm in the study eye

• Female subjects of childbearing potential and their male partners must both use ahighly effective contraception method during the study

Exclusion Criteria:

• Any clinically significant slit lamp finding

• Any ongoing ocular infection (bacterial, viral or fungal) or active ocularinflammation

• Best-corrected visual acuity ≥0.7 logarithm of the minimum angle of resolution

• Any keratorefractive surgery within the last 12 months

• Any intraocular or extraocular surgery within 3 months

• Any blepharoplasty or corneal transplant in either eye

• Any form of punctual, or intracanalicular occlusion in either eye

• History or presence of any ocular disorder that may interfere with study results