Testing the Efficacy of 100mg Vitamin-B6 Daily for Sensory Reactivity in Autism

Last updated: December 3, 2024
Sponsor: University of Reading
Overall Status: Active - Recruiting

Phase

N/A

Condition

Autism

Autism Spectrum Disorder (Asd)

Treatment

Placebo

Pyridoxal 5'-Phosphate (100 mg)

Clinical Study ID

NCT06234501
UREC23/27
  • Ages 18-60
  • All Genders

Study Summary

This clinical trial aims to explore the effect of Vitamin B6 supplementation on anxiety sensory hyperreactivity in autistic adults. Researchers will compare a placebo group to high-dose Vitamin-B6 to see if vitamin B6 reduce anxiety and sensory reactivity differences in autism.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Between the ages of 18 to 60

  • With a diagnosis of autism

Exclusion

Exclusion Criteria:

  • Taking any supplement that contains more than 2mg of Vitamin B6 or taking GABAagonist drugs

  • Have a medical history of peripheral neuropathy

  • lactose intolerance (placebo tablet is lactose based)

Study Design

Total Participants: 40
Treatment Group(s): 2
Primary Treatment: Placebo
Phase:
Study Start date:
November 08, 2024
Estimated Completion Date:
October 31, 2025

Study Description

The main question it aims to answer is:

  • Does high-dose Vitamin B6 supplementation reduce sensory hyperreactivity differences in autism?

  • Does high-dose Vitamin B6 supplementation reduce anxiety differences in autism?

  • Explore the effects of vitamin B6 on sleep quality, Attention Deficit Hyperactivity Disorder (ADHD) scores, and various visual perception tasks that are indicative of GABAergic activity

Connect with a study center

  • University of Reading

    Reading, RG6 6AL
    United Kingdom

    Active - Recruiting

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