A Study of LY3841136 in Japanese Participants With Obesity or Overweight

Inclusion Criteria:

• Male or female participants who agree to contraception requirements

• Have a body mass index (BMI) within the range of 27 to 40 kg/m², inclusive

• Have had a stable weight for the 3 months

Exclusion Criteria:

• Have a history of significant atopy (severe allergic manifestations), multiple orsevere drug allergies, or severe posttreatment hypersensitivity reactions

• Have a history or presence of psychiatric disorders, including a history of majordepressive disorder or severe psychiatric disorders such as schizophrenia, bipolardisorder within the last 3 years

• Have been diagnosed with Type 1 or Type 2 Diabetes Mellitus

• Have a history of chronic medical conditions involving the heart, liver, or kidneys

• Have a history of any malignancy within the past 5 years

• Have a history or presence of a GI disorder

• Have had within the last 6 months, or plan to have during the study, a device-basedor surgical treatment use for obesity

• Have been treated, or plan to be treated, with prescription medications or othernon-approved drugs intended to promote weight loss, within 3 months prior toscreening

• For participants in Part B, have previously received tirzepatide within 6 monthsprior to screening

• For participants in Part B, have a personal or family history of medullary thyroidcarcinoma, or have multiple endocrine neoplasia syndrome type 2