MyDiaMate For Remission Of Diabetes Distress In Type 1 Diabetes (MyREMEDY)

Last updated: May 8, 2024
Sponsor: Maartje de Wit
Overall Status: Active - Recruiting

Phase

N/A

Condition

Diabetes Mellitus, Type 1

Diabetes And Hypertension

Diabetes Prevention

Treatment

MyDiaMate

Clinical Study ID

NCT06308549
2023.0714
  • Ages > 18
  • All Genders

Study Summary

In the MyREMEDY study the investigators research whether the MyDiaMate self-help application is effective in strengthening the mental health of adults with type 1 diabetes in comparison with care as usual. The MyREMEDY study takes place in four countries: The Netherlands, United Kingdom, Spain, and Germany.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • At least 18 years old at signing the informed consent form
  • Type 1 diabetes diagnosis at least 6 months ago
  • Having access to the internet and a smartphone/tablet/laptop'/computer for the entiretime of study participation
  • Experiencing diabetes distress (checked during a phone call between research assistantand participant. The condition is met if the participant has an average score of ≥2 onthe 2-item Diabetes Distress Scale (DDS-2), representing clinically meaningfuldiabetes distress)

Exclusion

Exclusion Criteria:

  • Having been diagnosed with a psychiatric disorder in the past 6 months for which theperson is under psychological/psychiatric treatment
  • Suicidality
  • Having started a treatment with psychotropic medication in the past 3 months
  • Illiteracy
  • Experience of cognitive problems that hamper using MyDiaMate or vision/auditoryproblems that are hindering in daily life
  • Prior use of MyDiaMate (only applicable to participants in the Netherlands)

Study Design

Total Participants: 660
Treatment Group(s): 1
Primary Treatment: MyDiaMate
Phase:
Study Start date:
April 03, 2024
Estimated Completion Date:
July 31, 2025

Study Description

Rationale: Type 1 diabetes is a disease that asks constant attention, self-care activities and responsibility from the diagnosed person for the duration of their entire life. Because of this constant burden, many people with type 1 diabetes experience mental health problems such as fatigue, excessive worrying about their blood glucose (especially about dangerously low blood glucose), or eating problems. However, most people with type 1 diabetes who experience such symptoms do not receive professional help. This can have multiple reasons. Oftentimes, the problems are not severe enough to be classified as a disorder. Some people also prefer to work on the problems on their own, at their own pace. For people who experience mental health problems around their diabetes and to support them individually with as little barriers as possible, MyDiaMate was developed.

Objective: To investigate the effectiveness of MyDiaMate in reducing mental health problems in adults with type 1 diabetes who experience distress related to their disease across four countries (NL, DE, UK, ES).

Study design and procedure: Multi-national randomised-controlled trial (intervention : wait-list control group, randomised 2:1 per country).

After screening has confirmed study participation, participants will:

  1. Complete the baseline assessment and be randomisation afterwards

  2. Use MyDiaMate for 3 months in case of intervention group membership, or get care as usual in case of waitlist control group membership

  3. At 3 months, all participants fill in the first follow-up assessment. Additionally, intervention group members will be asked about their satisfaction with and opinion on MyDiaMate (questionnaire and interviews).

  4. All participants then receive access to MyDiaMate for the remaining 3 months of the study.

  5. At 6 months, all participants complete the second follow-up assessment. Afterwards, the study ends for all participants and access to MyDiaMate is revoked.

Study population: Adults with type 1 diabetes who have been diagnosed more than 6 months ago and who experience distress in relation to their type 1 diabetes.

Intervention: The intervention group receives access to the online self-help programme MyDiaMate for 6 months. MyDiaMate is focused on mental health in type 1 diabetes. It includes psychoeducation and teaches coping strategies that are based on cognitive-behavioural therapy concepts. Moreover, videos in which people with type 1 diabetes talk about their experiences in coping with the disease are embedded in MyDiaMate. MyDiaMate users can also choose to make use of diaries and a module that helps with setting realistic goals. MyDiaMate can be accessed via a private mobile phone, tablet, or laptop/computer whenever wished. Because MyDiaMate is self-help, there is no schedule in when/how much participants should access MyDiaMate. Participants can make use of MyDiaMate as much as they want to, in a way that suits them best personally. Members in the waitlist control group receive access to MyDiaMate after 3 months, for 3 months, if so wished. They too can make use of MyDiaMate in a way that fits their personal time and needs best.

Main study parameters/endpoints: The main study outcome is change in diabetes distress in the intervention group between the baseline and the 3 months assessment. Secondary study outcomes are changes in emotional well-being, psychological self-efficacy in relation to diabetes, social engagement, and fatigue between the baseline and the 3 months assessment in participants from the intervention group. Moreover, in line with the secondary objective, the investigators will make use of MyDiaMate log data such as time spent in MyDiaMate and frequency of use in participants of the intervention group across the first 3 months and investigate in relation to the main and secondary outcomes as well as descriptive data such as age or gender, for which subgroup of MyDiaMate users the application programme is most effective.

Nature and extent of the burden and risks associated with participation, benefit and group relatedness: There are no risks related to use of MyDiaMate. The burden of study participation is low, as participants are not instructed to use MyDiaMate in a certain way/intensity and filling in the non-invasive study questionnaires takes around 2 hr in total and is spread across 6 months. Both the intervention and control group have access to MyDiaMate during study participation (for 6 months in case of intervention group membership, for 3 months after 3 months in case of wait-list control group membership). Study participants benefit from study participation because they receive access to MyDiaMate, which may possibly help them with improving the diabetes-related mental health and teaches a variety of type 1 diabetes specific coping strategies, all of which is based on well-researched concepts of psychoeducation and cognitive behavioural therapy.

Connect with a study center

  • Forschungsinstitut Diabetes-Akademie Bad Mergentheim

    Bad Mergentheim, Baden-Württemberg 97980
    Germany

    Active - Recruiting

  • Amsterdam UMC

    Amsterdam, Noord-Holland 1081HV
    Netherlands

    Active - Recruiting

  • Universidad de Málaga

    Málaga, 29071
    Spain

    Site Not Available

  • King's College London

    London, WC2R 2LS
    United Kingdom

    Site Not Available

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.