Male Supplements for Sperm Quality and Aging

Last updated: August 1, 2024
Sponsor: Kaohsiung Veterans General Hospital.
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

Male supplement

Clinical Study ID

NCT06339996
KSVGH24-CT1-10
  • Ages 30-50
  • Male
  • Accepts Healthy Volunteers

Study Summary

This study investigates the effects of a new supplement on sperm quality in men with poor sperm quality. Fifty patients will receive the supplement for three months, followed by semen analysis and assessment of sperm aging and mitochondrial function. Changes in sexual function and aging symptoms will also be evaluated.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Not meet the criteria of the 6th edition of the WHO manual for human semen analysis

  • BMI:18-30 kg/m2

Exclusion

Exclusion Criteria:

  • Azoospermia

  • Varicocele

  • Chromosome anomaly

  • Malignancy

  • Using hormone therapy or supplements in recent 3 months

Study Design

Total Participants: 50
Treatment Group(s): 1
Primary Treatment: Male supplement
Phase:
Study Start date:
March 26, 2024
Estimated Completion Date:
December 31, 2025

Study Description

Due to modern lifestyle factors such as high work pressure, stressful routines, and environmental pollution, there has been a significant decline in sperm quality among men, potentially leading to infertility. In response, various supplements have emerged claiming to enhance sperm quality. This prospective investigation aims to determine the efficacy of a new supplement in improving sperm quality among patients with poor sperm quality. The study will enroll 50 patients undergoing semen analysis at our reproductive center, administering the supplement over a three-month treatment period to those identified with poor sperm quality. Subsequent semen analysis will be conducted, alongside assessments of sperm mitochondrial metabolic function before and after supplement administration. Sexual function and aging symptoms will also be evaluated using the International Index of Erectile Function (IIEF-5) and the Aging Males Symptoms Scale (AMS) before and after the supplementation period. The study aims to compare differences in semen analysis, sperm mitochondrial metabolic function, sexual function, and aging symptoms before and after supplementation.

Connect with a study center

  • Kaohsiung Veterans General Hospital

    Kaohsiung,
    Taiwan

    Active - Recruiting

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