A Brief Intervention for Cannabis Use

Last updated: April 7, 2025
Sponsor: Medical University of South Carolina
Overall Status: Active - Recruiting

Phase

N/A

Condition

Substance Abuse

Treatment

Bloom

Values in Action (VIA)

Health Education (HealthEdu)

Clinical Study ID

NCT06395389
Pro00133931
K23DA058077
K12DA031794
  • Ages 18-25
  • All Genders

Study Summary

The purpose of this study is to compare two brief interventions targeting potentially problematic cannabis use in emerging adults (ages 18-25). Brief interventions are two 40-50 minute sessions separated by 1 week. Eligible emerging adults will complete a detailed cannabis assessment (biological and self-report), followed by one of the two brief interventions, and three follow-up assessments: one immediately after the second session and at 1- and 3-months post-intervention. Assignment to the brief intervention is random. Salivary samples will be collected at baseline, post-intervention, and both follow-ups, for a total of 4 samples, to be tested for tetrahydrocannabinol (THC) and cannabidiol (CBD).

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Ages 18-25

  • Self-Report report cannabis use on at least 20 days of the past 30 days.

  • Completion of an Intake Visit (PRO #94743)

  • Submit a positive urine cannabinoid test during the Intake Visit

Exclusion

Exclusion Criteria:

  • Currently engaged in substance use treatment for any type of substance use orcurrently treatment seeking

  • History of substance use treatment for any type of substance

  • Severe alcohol use disorder or presence of any substance use disorder (SUD)requiring a higher level of care

  • Significant or acutely unstable medical or psychiatric problems (i.e., psychosis,mania) that would contraindicate research procedures, interfere with safety,compromise data integrity, or preclude consistent study participation

  • Significant risk of suicide or homicide

Study Design

Total Participants: 62
Treatment Group(s): 3
Primary Treatment: Bloom
Phase:
Study Start date:
October 18, 2024
Estimated Completion Date:
May 31, 2029

Study Description

Cannabis is the most widely used federally illicit substance among emerging adults (age 18-25) in the U.S., and frequent cannabis use is associated with myriad long-term health, social, and academic/occupational consequences. Despite this, rates of perceived risk of daily/regular cannabis use have steadily declined over the past two decades, and this is associated with increased frequency of use, a risk for for Cannabis Use Disorder (CUD). Brief interventions (BIs) are among the most frequently used approaches for addressing problematic or potentially problematic substance use in non-treatment-seeking adolescents and young adults. Although several cannabis brief interventions have been developed and tested to date, meta-analyses indicate that the efficacy of these interventions for emerging adults is mixed and the quality of studies is low, suggesting that novel approaches and rigorous methodology are necessary to improve efficacy. The current study will evaluate the feasibility, acceptability, and preliminary efficacy of a novel cannabis BI for emerging adults who frequently use cannabis.

Connect with a study center

  • Medical University of South Carolina

    Charleston, South Carolina 29425
    United States

    Active - Recruiting

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