Cultural Adaptation of EMDR for Major Depressive Disorder and Compaire Its Online and Face-to-Face Testing

Last updated: January 21, 2025
Sponsor: Khushal Khan Khattak Univeristy, Karak, Pakistan
Overall Status: Active - Recruiting

Phase

N/A

Condition

Depression (Adult And Geriatric)

Depression (Major/severe)

Depression

Treatment

Online EMDR Psychotherapy

EMDR Psychotherapy

Clinical Study ID

NCT06439043
1213
  • Ages 20-50
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

The present study aims to develop a culturally and methodologically adapted EMDR therapy protocol, determine its treatment fidelity, and then clinically test its efficacy in the treatment of Major Depressive Disorder in Pakistan by utilizing both in-person and online modalities of EMDR therapy.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. The patient should exhibit symptoms of Major Depressive Disorder.

  2. Male and female patients will be chosen equally.

  3. Patients between the ages of 20 and 50 will be selected.

  4. Patients should preferable be "treatment-naïve," meaning they have no recent historyof any psychotherapy or medication.

Exclusion

Exclusion Criteria:

a. There must be no significant neuropsychological or cognitive disorders among the patients

Study Design

Total Participants: 90
Treatment Group(s): 2
Primary Treatment: Online EMDR Psychotherapy
Phase:
Study Start date:
January 01, 2025
Estimated Completion Date:
September 30, 2025

Study Description

Background and Aim: Major Depressive Disorder(MDD) is a globally leading cause of disability. Currently, psychotherapies like Eye Movement Desensitization and Reprocessing(EMDR) and Cognitive Behavioral Therapy(CBT) are widely available. Since EMDR originated in the United States, it may not be completely appropriate for non-Western countries like Pakistan, necessitating possible modifications. Moreover, therapists have long practiced face-to-face EMDR, but recently, online EMDR modalities have emerged. Nonetheless, it is surprising that there is a dearth of research not only on adaptations of EMDR in Pakistan but also on testing its clinical efficacy, particularly its online modalities. Considering this, the present study aims to develop a culturally and methodologically adapted EMDR therapy protocol, and clinically evaluate its efficacy in treating MDD in Pakistan by comparatively administering it through in-person and online modalities. Methods: This study will employ a mixed mode Randomized Controlled Trial design with a consecutive sample of (n=90). Patients will be treated by using adapted EMDR therapy protocol. Patients will be randomly allocated to in-person and online modes of EMDR. Various qualitative methods and quantitative techniques will be employed to data. Conclusion: This study is likely to make significant contributions by delivering insights about how to develop culturally and methodologically adapted EMDR. This study will extend our knowledge about the comparative effectiveness of EMDR in Pakistan.

Connect with a study center

  • KKKUk

    Kohat, 27200
    Pakistan

    Active - Recruiting

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.